ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2020
Prevalence of obstructive sleep apnea in patients with rheumatoid arthritis.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sleep-related problems among patients with rheumatoid arthritis in the World Health Organization Eastern Mediterranean region: a systematic review and meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Review
- Obstructive Sleep Apnea in Psoriatic Arthritis: Clinical Characteristics and Comorbidities.Biomedicines · 2026Article
- Linking sleep apnea and arthritis in the National Alzheimer Coordinating Center Cohort: A cross-sectional analysis.Medicine · 2026Article
- Using objective measures of physical activity, sleep, and breathing for disease profiling of patients with systemic lupus erythematosus and Sjögren's disease.Frontiers in digital health · 2026Article
- The Impact of Insomnia on the Clinical Course and Treatment Outcomes of Rheumatoid Arthritis.Biomedicines · 2025Review
- The causal relationship between obstructive sleep apnea and rheumatic disease: A bidirectional Mendelian randomization study.Rheumatology and immunology research · 2025Article
- Sleep duration and the risk of new-onset arthritis in middle-aged and older adult population: results from prospective cohort study in China.Frontiers in public health · 2024Article
- Heat of the night: sleep disturbance activates inflammatory mechanisms and induces pain in rheumatoid arthritis.Nature reviews. Rheumatology · 2023Review
- Systemic Lupus Erythematous and Obstructive Sleep Apnea: A Possible Association.Life (Basel, Switzerland) · 2023Article
- A Review of a Recent Meta-Analysis Study on Obstructive Sleep Apnea.Journal of rhinology : official journal of the Korean Rhinologic Society · 2022Review
- Association Between Sleep Traits and Rheumatoid Arthritis: A Mendelian Randomization Study.Frontiers in public health · 2022Article
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Authors and funding
10 authors.
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Abstract
STUDY
objectivesAlthough previous studies suggested an increased prevalence of obstructive sleep apnea (OSA) among patients with rheumatoid arthritis (RA), no existing large prospective study has addressed this association using objective measures. This study aims to assess the prevalence of OSA using polysomnography (PSG) in patients with RA and its relationship with RA activity.
methodsPatients with RA who presented at the rheumatology clinic at a university hospital from 2017 to 2018 were eligible. In the first stage, data from the Disease Activity Score 28, Berlin questionnaire, and Epworth Sleepiness Scale were obtained, along with personal data and a comprehensive medical history. The second stage involved a case-control study confirming OSA with PSG. OSA was defined as an apnea-hypopnea index (AHI) ≥ 5 events/h, whereas patients with an AHI ≥ 15 events/h were categorized as having moderate-severe OSA.
resultsIn total, 199 patients with RA were recruited, 110 patients (55%) underwent PSG, and 5 were excluded. The mean age was 48.93 ± 12.7 years, and the mean body mass index was 31.70 ± 9.74 kg/m²; 94% were female. In total, 67 participants (33.2%) were at high risk for OSA (36 [55.4%] underwent PSG), whereas 132 (66.8%) were at low risk (69 [51.5%] underwent PSG). The estimated prevalence of OSA (AHI ≥ 5 events/h) in the whole population was 58.1%, whereas the prevalence of moderate-to-severe OSA (AHI ≥ 15) was 22.9%.
conclusionsThis prospective PSG-based study demonstrated that OSA is more common in patients with RA than in the general population, but there appears to be no relationship with disease activity.
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