ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2020
Primary site identification in children with obstructive sleep apnea by computational fluid dynamics analysis of the upper airway.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Upper airway dimensions in pediatric obstructive sleep-disordered breathing: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- Application of numerical simulation of upper airway flow field in pediatric obstructive sleep apnea with adenoid hypertrophy.Quantitative imaging in medicine and surgery · 2026Article
- Biomechanical analysis of upper airway airflow characteristics in children.Sleep & breathing = Schlaf & Atmung · 2026Article
- Shape Matters: Computational Fluid Dynamics Analysis of Epiglottis Shape Influence on Airway Collapse in Obstructive Sleep Apnea Patients.Biomedicines · 2026Article
- Anatomical Determinants of Tracheal Breathing Sounds: A Computational Study of Airway Narrowing and Obstructive Sleep Apnea.Diagnostics (Basel, Switzerland) · 2025Article
- Mechanical mechanism study of upper airway collapse and twin block treatment in a patient with mandibular retrognathia using fluid-structure interaction simulation.BMC oral health · 2025Article
- Low Tongue Posture Improvement Effect of Orofacial Myofunctional Therapy Comprehensive Study of Nasal Ventilation Condition Using Computational Fluid Dynamics and Dental Arch Morphology.Orthodontics & craniofacial research · 2025Article
- Simulation of Central Airway Gas Flow Dynamics During Conventional and Multifrequency Ventilation.Journal of biomechanical engineering · 2025Article
- Numerical simulation and functional evaluation of upper airway before and after twin block treatment with different respiratory pathways.Clinical oral investigations · 2025Article
- Upper airway hydrodynamics changes after molar distalization with aligners in adult patients.Clinical oral investigations · 2024Article
- Modeling Realistic Geometries in Human Intrathoracic Airways.Diagnostics (Basel, Switzerland) · 2024Review
- Correlation between polysomnographic parameters and volumetric changes generated by maxillomandibular advancement surgery in patients with obstructive sleep apnea: a fluid dynamics study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Observational
- Comparison of anatomic and aerodynamic characteristics of the upper airway among edentulous mild, moderate, and severe obstructive sleep apnea in older adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Critical to Know Pcrit: A Review on Pharyngeal Critical Closing Pressure in Obstructive Sleep Apnea.Frontiers in neurology · 2022Review
- Aerodynamic characteristics in upper airways among orthodontic patients and its association with adenoid nasopharyngeal ratios in lateral cephalograms.BMC medical imaging · 2021Article
- Effect of adenoids and tonsil tissue on pediatric obstructive sleep apnea severity determined by computational fluid dynamics.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Detailed evaluation of the upper airway in the Dp(16)1Yey mouse model of Down syndrome.Scientific reports · 2020Article
- Does nasal surgery improve multilevel surgical outcome in obstructive sleep apnea: A multicenter study on 735 patients.Laryngoscope investigative otolaryngology · 2020Article
- The collapsing anatomical structure is not always the primary site of flow limitation in obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Characterization of upper airway airflow dynamics in young adults with isolated Robin sequence: An exploratory investigation.Journal of oral biology and craniofacial researchArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesObstructive sleep apnea (OSA) is a respiratory disorder caused by the obstruction of the upper airway during sleep. The identification of the primary site of OSA is essential to determine treatment strategy. This study aimed to establish computational fluid dynamics (CFD) analysis for determining the clinical severity of OSA and the primary site of OSA.
methodsTwenty children (mean age, 6 years) were divided into OSA and control groups according to their apnea-hypopnea index. Three-dimensional airways were constructed from computed tomography data. The pharyngeal airway morphology and the pressure and velocity of the upper airway were evaluated using CFD analysis.
resultsThe maximum velocity and negative pressure of the upper airway in the OSA group were significantly correlated with the severity of OSA (r
conclusionsCFD analysis allows both the evaluation of the disease severity of OSA and the identification of the primary site of OSA in children. The primary site of OSA is not necessarily the same as the collapsible conduit site; therefore, CFD analysis can be used to identify the appropriate intervention for treating OSA.
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