Evidence map›Paper›PMID 31992275›Full record

Observational studyBMC endocrine disorders2020

Profile and factors associated with glycaemic control of patients with type 2 diabetes in Greece: results from the diabetes registry.

Kyriakos Souliotis, Anastasios Koutsovasilis, Georgia Vatheia, Christina Golna, Sofia Nikolaidi, Erifili Hatziagelaki, Kalliopi Kotsa, Theocharis Koufakis, Andreas Melidonis, Athanasia Papazafiropoulou and 3 more

Open access · goldAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC endocrine disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Whole Exome Sequencing Study in a Family with Type 2 Diabetes Mellitus.International journal of general medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Kyriakos SouliotisDepartment of Social and Education Policy, University of Peloponnese, Corinth, Greece. info@ksouliotis.gr.ORCID https://orcid.org/0000-0003-1624-9444
Anastasios Koutsovasilis3rd Department of Internal Medicine and Diabetes Center, General Hospital of Nikaia, Piraeus, Greece.
Georgia VatheiaDepartment of Social and Education Policy, University of Peloponnese, Corinth, Greece.
Christina GolnaInnowth Ltd, Larnaca, Cyprus.
Sofia NikolaidiDepartment of Social and Education Policy, University of Peloponnese, Corinth, Greece.
Erifili Hatziagelaki2nd Department of Internal Medicine-Propaedeutic, Research Institute and Diabetes Center "Attikon" University Hospital Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Kalliopi KotsaDivision of Endocrinology and Metabolism and Diabetes Center, 1st Department of Internal Medicine, Medical School, Aristotle University, AHEPA University Hospital, Thessaloniki, Greece.ORCID https://orcid.org/0000-0003-2376-740X
Theocharis KoufakisDivision of Endocrinology and Metabolism and Diabetes Center, 1st Department of Internal Medicine, Medical School, Aristotle University, AHEPA University Hospital, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-5853-1352
Andreas Melidonis1st Department of Internal Medicine and Diabetes Center, Tzaneio General Hospital of Piraeus, Athens, Greece.
Athanasia Papazafiropoulou1st Department of Internal Medicine and Diabetes Center, Tzaneio General Hospital of Piraeus, Athens, Greece.
Nikolaos Tentolouris1st Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece.
Evangelia Siami1st Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece.
Alexios Sotiropoulos3rd Department of Internal Medicine and Diabetes Center, General Hospital of Nikaia, Piraeus, Greece.
National and Kapodistrian University of Athens · GRUniversity of Peloponnese · GRAHEPA University Hospital · GRGeneral Hospital of Nikea · GRTzaneion General Hospital · GR

Funding

Novo Nordisk Hellas 0394
6 · The paper itself

Abstract

backgroundStrict glycaemic control early in the treatment process has been shown to reduce the occurrence of micro- and macro- vascular complications of diabetes in the long-term. Thus, treatment guidelines advise early intensification of treatment to achieve glycaemic control goals. However, evidence in Greece suggests that, despite guideline recommendations, glycaemic control among patients with T2DM remains challenging. This study presents the demographic and clinical characteristics of patients with T2DM in Greece using data from an electronic registry designed specifically for this treatment category and investigates the factors that are independently associated with glycaemic control.

methodsThis is a multi-center, observational, cross-sectional study to investigate epidemiological and clinical factors affecting glycaemic control among patients with T2DM in Greece. Data was collected via a web-based disease registry, the Diabetes Registry, which operated from January 1st to December 31st, 2017. Five large specialized diabetes centers operating in Greek hospitals participated in the study.

resultsData for 1141 patients were retrieved (aged 63.02 ± 12.65 years, 56.9% male). Glycaemic control (Hb1Ac < 7%) was not achieved in 57.1% of patients. Factors independently associated with poor glycaemic control were: family history of diabetes [OR: 1.53, 95% CI: 1.06-2.23], BMI score between 25 to 30 [OR: 2.08, 95% CI: 1.05-4.13] or over 30 [OR: 2.12, 95% CI 1.12-4.07], elevated LDL levels [OR: 1.53, 95% 1.06-2.21] and low HDL levels [OR: 2.12, 95% CI: 1.44-3.12]. Lastly, use of injectable antidiabetic agents (in monotherapy or in combination) was less likely to be associated with poor glycaemic control versus treatment with combination of oral and injectable agents [OR: 0.50, 95% CI: 0.24-1.01]. This association was found to be marginally statistically significant.

conclusionInadequate lipid control, family history of diabetes and presence of obesity (ΒΜΙ ≥ 30 kg/m

Indexed as

BiomarkersBlood GlucoseCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGlycated HemoglobinHumansHyperglycemiaHypoglycemiaHypoglycemic AgentsMaleMiddle AgedPrognosisRegistriesBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsGlycaemic controlProfileRegistryType 2 diabetes mellitus

Identifiers

PMID31992275
PMCPMC6986011
OpenAlexW3008896641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.