ArticleBMC cancer2020
Efficacy and safety of self-expanding metallic stent placement followed by neoadjuvant chemotherapy and scheduled surgery for treatment of obstructing left-sided colonic cancer.
Article in BMC cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Laparoscopic versus open surgery in obstructive colorectal cancer patients following stents placement: a comprehensive meta-analysis of cohort studies.Surgical endoscopy · 2024Pooled it
- Survival and safety after neoadjuvant chemotherapy or upfront surgery for locally advanced colon cancer: meta-analysis.The British journal of surgery · 2024Pooled it
- Trial
- Outcomes of colonic stent as a bridge to surgeryWorld journal of gastrointestinal surgery · 2025Article
- Article
- Circulating cell-free DNA and tumor DNA dynamics in obstructive colon cancer undergoing neoadjuvant chemotherapy following stent placement.Frontiers in surgery · 2025Article
- Oncologic investigation of the interval from stent placement to surgery in patients with obstructive colorectal cancer.Surgery today · 2024Article
- The ELECLA trial: A multicentre randomised control trial on outcomes of neoadjuvant treatment on locally advanced colon cancer.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024Article
- The optimal surgery timing after stenting in colorectal cancer patients with malignant obstruction: additionally compared with emergency surgery.World journal of surgical oncology · 2023Article
- Current practice for the treatment of obstructive left-sided colon cancer in China: a nationwide cross-sectional survey.Surgery today · 2023Article
- Oncologic impact of colonic stents for obstructive left-sided colon cancer.World journal of clinical oncology · 2023Review
- Impact of endoscopic metallic stent placement and emergency surgery on detection of viable circulating tumor cells for acute malignant left-sided colonic obstruction.World journal of surgical oncology · 2023Article
- Safety and feasibility of neoadjuvant chemotherapy as a surgical bridge for acute left-sided malignant colorectal obstruction: a retrospective study.BMC cancer · 2022Article
- Efficacy of Laparoscopic Radical Resection Combined with Neoadjuvant Chemotherapy and Its Impact on Long-Term Prognosis of Patients with Colorectal Cancer.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Short-term effect of different time interval between self-expanding metallic stent and surgery for left-sided malignant colorectal obstruction.Frontiers in gastroenterology (Lausanne, Switzerland) · 2022Article
- Colon cancer patient with long-term colon stent placement: Case report and literature review.Frontiers in oncology · 2022Article
- Management of obstructive colon cancer: Current status, obstacles, and future directions.World journal of gastrointestinal oncology · 2021Article
- Biopsy sampling during self-expandable metallic stent placement in acute malignant colorectal obstruction: a narrative review.World journal of surgical oncology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThis study aimed to evaluate the safety and feasibility of self-expanding metallic stent (SEMS) followed by neoadjuvant chemotherapy prior to elective surgery for obstructing left-sided colon cancer.
methodsEleven consecutive patients with obstructing left-sided colon cancer between May 2014 and November 2015 were included retrospectively. All patients received SEMS followed by neoadjuvant chemotherapy. The primary outcome measure was stoma and laparoscopic surgery.
resultsChemotherapy was with two cycles of CAPOX (54.5%) or three cycles mFOLFOX6 (45.5%). Median serum albumin and hemoglobin levels before surgery were significantly higher than before neoadjuvant chemotherapy (p = 0.01 and p = 0.008 respectively) and before SEMS (p = 0.01 and p = 0.003 respectively). Median bowel wall thickness proximal to the upper edge of tumor was significantly more before neoadjuvant chemotherapy than before stent (p = 0.003), and significantly less before surgery than before neoadjuvant chemotherapy (p = 0.003). No patient underwent stoma creation. Laparoscopic surgery was performed in nine (81.8%) patients. No local recurrence or metastases developed over median cancer-specific follow-up of 44 months (range, 37-55 months).
conclusionSEMS followed by neoadjuvant chemotherapy prior to elective surgery appears to be safe and well tolerated in patients with obstructing left-sided colon cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.