Evidence map›Paper›PMID 31992206›Full record

ArticleBMC cardiovascular disorders2020

Alterations in gut microbiota of abdominal aortic aneurysm mice.

Jiahe Xie, Weiling Lu, Lintao Zhong, Yuhua Hu, Qingrui Li, Rongming Ding, Zhonggao Zhong, Ziyou Liu, Hai Xiao, Dongming Xie and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Evidence for a Role of Gut Microbiota and Probiotics in Aneurysmal Pathogenesis and Possible Therapeutics: A Systematic Review of the Literature.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
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  20. Impact ofBioscience of microbiota, food and health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Jiahe XieDepartment of Cardiology, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Weiling LuDepartment of Cardiology, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Lintao ZhongDepartment of Cardiology, Zhuhai Hospital, Jinan University, Zhuhai, China.
Yuhua HuDepartment of Cardiology, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Qingrui LiDepartment of Cardiology, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Rongming DingDepartment of Cardiology, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Zhonggao ZhongDepartment of Cardiology, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Ziyou LiuKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, People's Republic of China.
Hai XiaoKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, People's Republic of China.
Dongming XieDepartment of Cardiology, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Guofu ZhengDepartment of Vascular Surgery, the Affiliated Ganzhou Hospital of Nanchang University, Guangzhou, China.
Bo YeDepartment of Vascular Surgery, the Affiliated Ganzhou Hospital of Nanchang University, Guangzhou, China.
Yiming ZhongDepartment of Cardiology, First Affiliated Hospital of Gannan Medical University, Ganzhou, China. yimingdoc@126.com.
Zuheng LiuState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China. john_lau@126.com.ORCID http://orcid.org/0000-0002-5087-0480
Gannan Medical University · CNNanchang University · CNNanfang Hospital · CNJinan University · CN

Funding

China Postdoctoral Science Foundation funded project 2019M652959Open Project of Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education XN201813Science and Technology Research Program of Department of Education of Jiangxi Province GJJ170850, GJJ180813 and GJJ170876the scientific research project of Gannan Medical University TD201704
6 · The paper itself

Abstract

backgroundThe gut microbiome plays an important role in various cardiovascular diseases, such as atherosclerosis and hypertension, which are associated with abdominal aortic aneurysms (AAAs).

methodsHere, we used 16S rRNA sequencing to explore gut microbiota in C57BL ApoE

resultsWe found that the gut microbiome was different between control and AAA mice. The results of correlation analysis between AAA diameter and the gut microbiome as well as LEfSe of the genera Akkermansia, Odoribacter, Helicobacter and Ruminococcus might be important in the progression of AAAs.

conclusionsAAA mice is subjected to gut microbial dysbiosis, and gut microbiota might be a potential target for further investigation.

Indexed as

Gastrointestinal MicrobiomeAngiotensin IIAnimalsAortic Aneurysm, AbdominalBacteriaDisease Models, AnimalDysbiosisFecesIntestinesMaleMice, Inbred C57BLMice, Knockout, ApoERibotypingAngiotensin IIAbdominal aortic aneurysmAkkermansiaGut microbiota

Identifiers

PMID31992206
PMCPMC6988222
OpenAlexW3006114636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.