ArticleProceedings. Biological sciences2020
Wetter climates select for higher immune gene diversity in resident, but not migratory, songbirds.
Article in Proceedings. Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Static Expression of Major Histocompatibility Complex Genes Across Life-Stages, Generations and Tissues in a Songbird.Molecular ecology · 2026Article
- Evolutionary Response Patterns of the RodentEcology and evolution · 2026Article
- Article
- MHC Diversity Across Time and Space.Ecology and evolution · 2025Review
- Constitutive immune function is not associated with fuel stores in spring migrating passerine birds.Ecology and evolution · 2024Article
- Assessing immune phenotypes using simple proxy measures: promise and limitations.Discovery immunology · 2024Article
- Ancient duplication, coevolution, and selection at the MHC class IIA and IIB genes of birds.Frontiers in immunology · 2023Article
- The structure of songbird MHC class I reveals antigen binding that is flexible at the N-terminus and static at the C-terminus.Frontiers in immunology · 2023Article
- Article
- Selection and demography drive range-wide patterns of MHC-DRB variation in mule deer.BMC ecology and evolution · 2022Article
- Adaptation and Cryptic Pseudogenization in Penguin Toll-Like Receptors.Molecular biology and evolution · 2022Article
- The Consequences of Our Changing Environment on Life Threatening and Debilitating Fungal Diseases in Humans.Journal of fungi (Basel, Switzerland) · 2021Review
- COVID-19 pandemic: the possible influence of the long-term ignorance about climate change.Environmental science and pollution research international · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathogen communities can vary substantially between geographical regions due to different environmental conditions. However, little is known about how host immune systems respond to environmental variation across macro-ecological and evolutionary scales. Here, we select 37 species of songbird that inhabit diverse environments, including African and Palaearctic residents and Afro-Palaearctic migrants, to address how climate and habitat have influenced the evolution of key immune genes, the major histocompatibility complex class I (MHC-I). Resident species living in wetter regions, especially in Africa, had higher MHC-I diversity than species living in drier regions, irrespective of the habitats they occupy. By contrast, no relationship was found between MHC-I diversity and precipitation in migrants. Our results suggest that the immune system of birds has evolved greater pathogen recognition in wetter tropical regions. Furthermore, evolving transcontinental migration appears to have enabled species to escape wet, pathogen-rich areas at key periods of the year, relaxing selection for diversity in immune genes and potentially reducing immune system costs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.