ArticleBiology letters2020
Host heterogeneity mitigates virulence evolution.
Article in Biology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 48 citations in OpenAlex.
- Prior pathogen exposure augments inter-individual heterogeneity in antibody levels and reinfection loads in a songbird-pathogen system.Scientific reports · 2026Article
- Host Prior Exposure Augments Gene Expression Heterogeneity of Both Host and Pathogen During In Vivo Infection.Molecular ecology · 2026Article
- Within-Host Environmental Heterogeneity Is Associated With Phenotypic but Not Genomic Diversity in Wolbachia Endosymbionts.Environmental microbiology reports · 2026Article
- Malaria parasites can optimize transmission investment by sensing two within-host cues.PLoS biology · 2025Article
- Superspreading and the evolution of virulence.PLoS computational biology · 2025Article
- Host prior exposure augments heterogeneity in gene expression in both host and pathogen duringbioRxiv : the preprint server for biology · 2025Article
- Reinfection with a Bacterial Pathogen Augments Heterogeneity in Host Disease Responses.Research square · 2025Article
- Within-host competition causes pathogen molecular evolution and perpetual microbiota dysbiosis.The ISME journal · 2025Article
- Evolution of parasite transmission dispersion.Royal Society open science · 2025Article
- Multispecies interactions and the community context of the evolution of virulence.Proceedings. Biological sciences · 2024Article
- Pathogen contingency loci and the evolution of host specificity: Simple sequence repeats mediate Bartonella adaptation to a wild rodent host.PLoS pathogens · 2024Article
- Fluctuating selection facilitates the discovery of broadly effective but difficult to reach adaptive outcomes in yeast.Evolution letters · 2024Article
- Genetic structure and Rickettsia infection rates in Ixodes ovatus and Haemaphysalis flava ticks across different altitudes.PloS one · 2024Article
- Hatchability ofPathogens (Basel, Switzerland) · 2023Article
- Interspecific host competition and parasite virulence evolution.Biology letters · 2023Article
- Genetic slippage after sex maintains diversity for parasite resistance in a natural host population.Science advances · 2022Article
- Genetic diversity and disease: The past, present, and future of an old idea.Evolution; international journal of organic evolution · 2022Article
- Defects in plant immunity modulate the rates and patterns of RNA virus evolution.Virus evolution · 2022Article
- Host genotype and genetic diversity shape the evolution of a novel bacterial infection.The ISME journal · 2021Article
- Host Genetic Diversity and Infectious Diseases. Focus on Wild Boar, Red Deer and Tuberculosis.Animals : an open access journal from MDPI · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parasites often infect genetically diverse host populations, and the evolutionary trajectories of parasite populations may be shaped by levels of host heterogeneity. Mixed genotype host populations, compared to homogeneous host populations, can reduce parasite prevalence and potentially reduce rates of parasite adaptation due to trade-offs associated with adapting to specific host genotypes. Here, we used experimental evolution to select for increased virulence in populations of the bacterial parasite
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.