Evidence map›Paper›PMID 31991927›Full record

ArticleInternational journal of molecular sciences2020

Endothelial response boosted by platelet lysate: the involvement of calcium toolkit.

Simona Martinotti, Mauro Patrone, Valeria Balbo, Laura Mazzucco, Elia Ranzato

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Reactive Oxygen Species and Endothelial CaInternational journal of molecular sciences · 2021
    Review
  6. Article
  7. Biomedicines · 2021
    Article
  8. Diphlorethohydroxycarmalol Isolated fromInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Simona MartinottiDiSIT- Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, 15121 Alessandria, Italy.
Mauro PatroneDiSIT- Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, 15121 Alessandria, Italy.
Valeria BalboLaboratorio Produzione Emocomponenti e Medicina Rigenerativa, SIMT - AO "SS Antonio e Biagio", 15121 Alessandria, Italy.
Laura MazzuccoLaboratorio Produzione Emocomponenti e Medicina Rigenerativa, SIMT - AO "SS Antonio e Biagio", 15121 Alessandria, Italy.
Elia RanzatoDiSIT- Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, 15121 Alessandria, Italy.
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

piemonte orientale ricerca locale 2019
6 · The paper itself

Abstract

Wound repair is a dynamic process during which crucial signaling pathways are regulated by growth factors and cytokines released by several kinds of cells directly involved in the healing process. However, the limited applications and heterogeneous clinical results of single growth factors in wound healing encouraged the use of a mixture of bioactive molecules such as platelet derivatives for best results in wound repair. An interesting platelet derivative, obtained from blood samples, is platelet lysate (PL), which has shown potential clinical application. PL is obtained from freezing and thawing of platelet-enriched blood samples. Intracellular calcium (Ca

Indexed as

Calcium SignalingAnimalsBlood PlateletsCell DifferentiationCell Line, TransformedCell MovementCell ProliferationCell SurvivalEndothelial CellsEndothelium, VascularMicecell calciumendothelial cellsplatelet lysateROSwound repair

Identifiers

PMID31991927
PMCPMC7036775
OpenAlexW3001136550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.