Evidence map›Paper›PMID 31991894›Full record

ArticleNutrients2020

Pomace Olive Oil Concentrated in Triterpenic Acids Restores Vascular Function, Glucose Tolerance and Obesity Progression in Mice.

Carmen Maria Claro-Cala, Jose Carlos Quintela, Marta Pérez-Montero, Javier Miñano, María Alvarez de Sotomayor, María Dolores Herrera, And Rosalía Rodríguez-Rodríguez

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Profiling of secondary metabolite and evaluation of anti-diabetic potency ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Carmen Maria Claro-CalaDepartment of Pharmacology, Pediatric and Radiology, Faculty of Medicine, University of Sevilla, E-41009 Sevilla, Spain.
Jose Carlos QuintelaNatac Biotech S.L., Electrónica 7, 28923 Alcorcón, Madrid, Spain.
Marta Pérez-MonteroBasic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, E-08195 Sant Cugat del Vallès, Spain.ORCID 0000-0001-9573-5330
Javier MiñanoDepartment of Pharmacology, Pediatric and Radiology, Faculty of Medicine, University of Sevilla, E-41009 Sevilla, Spain.
María Alvarez de SotomayorDepartamento de Farmacología, Facultad de Farmacia, Universidad de Sevilla, E-41012 Sevilla, Spain.ORCID 0000-0001-8466-1698
María Dolores HerreraDepartamento de Farmacología, Facultad de Farmacia, Universidad de Sevilla, E-41012 Sevilla, Spain.
And Rosalía Rodríguez-RodríguezBasic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, E-08195 Sant Cugat del Vallès, Spain.
Universidad de Sevilla · ESUniversitat Internacional de Catalunya · ES

Funding

Ministerio de Ciencia, Innovación y Universidades PCI2018-092997 /AEIMinisterio de Ciencia, Innovación y Universidades SAF2017-82813-C3-3-R
6 · The paper itself

Abstract

Pomace olive oil, an olive oil sub-product, is a promising source of bioactive triterpenoids such as oleanolic acid and maslinic acid. Considering the vascular actions of pomace olive oil and the potential effects of the isolated oleanolic acid on metabolic complications of obesity, this study investigates for the first time the dietary intervention with a pomace olive oil with high concentrations of the triterpenic acids (POCTA), oleanolic and maslinic acid, during diet-induced obesity in mice. The results demonstrate that obese mice, when switched to a POCTA-diet for 10 weeks, show a substantial reduction of body weight, insulin resistance, adipose tissue inflammation, and particularly, improvement of vascular function despite high caloric intake. This study reveals the potential of a functional food based on pomace olive oil and its triterpenic fraction against obesity progression. Our data also contribute to understanding the health-promoting effects attributable to the Mediterranean diet.

Indexed as

Diet, MediterraneanVasoconstrictionVasodilationAdiposityAnimalsAorta, ThoracicBiomarkersBlood GlucoseDiet, High-FatDisease Models, AnimalDisease ProgressionInsulin ResistanceMaleMice, Inbred C57BLObesityOleanolic AcidBiomarkersBlood Glucosemaslinic acidOleanolic AcidOlive OilTriterpenesmaslinic acidMediterranean dietobesityoleanolic acidpomace olive oilvascular function

Identifiers

PMID31991894
PMCPMC7071211
OpenAlexW3001192597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.