Evidence map›Paper›PMID 31991892›Full record

ArticleNutrients2020

The 25(OH)Vitamin D Status Affected the Effectiveness of Oligo Fucoidan in Patients with Chronic Hepatitis B Virus Infection with Immune Tolerance Phase.

Wang-Sheng Ko, Fang-Ping Shen, Chia-Ju Shih, Ya-Ling Chiou

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wang-Sheng KoDepartment of Nutrition, Master of Biomedical Nutrition Program, HungKuang University, Taichung43302, Taiwan.
Fang-Ping ShenDepartment of Nutrition, Master of Biomedical Nutrition Program, HungKuang University, Taichung43302, Taiwan.
Chia-Ju ShihDepartment of Nutrition, Master of Biomedical Nutrition Program, HungKuang University, Taichung43302, Taiwan.
Ya-Ling ChiouDepartment of Nutrition, Master of Biomedical Nutrition Program, HungKuang University, Taichung43302, Taiwan.
Hungkuang University · TWKuang Tien General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hepatitis B virus (HBV) infection is a serious public health issue. Vitamin D is involved in various pathophysiological mechanisms as an immune modulator and the deficiency rate of vitamin D is prevalent in chronic liver disease. Fucoidan exerts anti-inflammatory, anticoagulant, antitumor, antimetastatic, and antiangiogenetic effects; however, its effect on the immune responses of HBV patients is unclear. This study investigated how 25(OH)Vitamin D status affected the effectiveness of oligo fucoidan in patients with HBV infection in the immune tolerance phase. Fifty-one patients received oligo fucoidan 4400 mg/day for 48 weeks. Flow cytometry was used to detect T lymphocyte markers (CD3

Indexed as

AdultBiomarkersDNA, ViralFemaleHepatitis BHepatitis B, ChronicHepatitis B e AntigensHost-Pathogen InteractionsHumansImmunologic FactorsMaleMiddle AgedPolysaccharidesT-LymphocytesTreatment OutcomeViral Load25-hydroxyvitamin DBiomarkersDNA, ViralfucoidanHepatitis B e AntigensImmunologic FactorsPolysaccharidesVitamin Dchronic hepatitis Boligo fucoidanT lymphocytesvitamin D

Identifiers

PMID31991892
PMCPMC7071272
OpenAlexW3002646516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.