Evidence map›Paper›PMID 31991845›Full record

ArticleCells2020

N6-Methyladenosine Regulates the Expression and Secretion of TGFβ1 to Affect the Epithelial-Mesenchymal Transition of Cancer Cells.

Jiexin Li, Feng Chen, Yanxi Peng, Ziyan Lv, Xinyao Lin, Zhuojia Chen, Hongsheng Wang

Abstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Review
  2. Article
  3. FTO-mediated mClinical and translational medicine · 2025
    Article
  4. Article
  5. The regulatory role of m6A in cancer metastasis.Frontiers in cell and developmental biology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Progression of mCell death discovery · 2024
    Review
  10. Review
  11. Article
  12. New insights into the regulation of METTL3 and its role in tumors.Cell communication and signaling : CCS · 2023
    Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Crosstalk among mJournal of hematology & oncology · 2022
    Review
  20. RNA mMolecular therapy : the journal of the American Society of Gene Therapy · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiexin LiDepartment of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Feng ChenDepartment of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Yanxi PengDepartment of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Ziyan LvDepartment of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Xinyao LinDepartment of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Zhuojia ChenSun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Hongsheng WangDepartment of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N6-methyladenosine (m

Indexed as

5' Untranslated RegionsAdenosineAnimalsCell MovementDown-RegulationEpithelial-Mesenchymal TransitionGene Knockdown TechniquesHeLa CellsHumansLung NeoplasmsMethyltransferasesMicePeptide Chain Elongation, TranslationalProtein BiosynthesisProtein StabilitySnail Family Transcription Factors5' Untranslated RegionsAdenosineMethyltransferasesMETTL3 protein, humanN-methyladenosineSNAI1 protein, humanSnail Family Transcription FactorsTransforming Growth Factor beta1EMTm6ATGFβ1

Identifiers

PMID31991845
PMCPMC7072279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.