Evidence map›Paper›PMID 31991835›Full record

ArticlePharmaceutics2020

Metal Organic Framework@Polysilsesequioxane Core/Shell-Structured Nanoplatform for Drug Delivery.

Liangyu Lu, Mengyu Ma, Chengtao Gao, Hongwei Li, Long Li, Fuping Dong, Yuzhu Xiong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liangyu LuCollege of Materials and Metallurgy, Guizhou University, Guiyang 550025, China.
Mengyu MaCollege of Materials and Metallurgy, Guizhou University, Guiyang 550025, China.
Chengtao GaoCollege of Materials and Metallurgy, Guizhou University, Guiyang 550025, China.
Hongwei LiCollege of Materials and Metallurgy, Guizhou University, Guiyang 550025, China.
Long LiCollege of Materials and Metallurgy, Guizhou University, Guiyang 550025, China.
Fuping DongCollege of Materials and Metallurgy, Guizhou University, Guiyang 550025, China.ORCID 0000-0002-5452-4964
Yuzhu XiongCollege of Materials and Metallurgy, Guizhou University, Guiyang 550025, China.

Funding

Guizhou Science and Technology Department (2019)1092, 2016123, and GZU201625National Natural Science Foundation of China 51663003
6 · The paper itself

Abstract

Modern pharmaceutics requires novel drug loading platforms with high drug loading capacity, controlled release, high stability, and good biocompacity. Metal-organic frameworks (MOFs) show promising applications in biomedicine owing to their extraordinarily high surface area, tunable pore size, and adjustable internal surface properties. However, MOFs have low stability due to weak coordinate bonding and limited biocompatibility, limiting their bioapplication. In this study, we fabricated MOFs/polysilsesquioxane (PSQ) nanocomposites and utilized them as drug carriers. Amine-functionalized MOF (UiO-66-NH

Indexed as

drug deliverymetal organic frameworkorganosilicapolysilsesquioxanesurface functionalization

Identifiers

PMID31991835
PMCPMC7076662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.