Evidence map›Paper›PMID 31991806›Full record

ArticleMolecules (Basel, Switzerland)2020

Design, Synthesis, Molecular Modelling and Anticancer Activities of New Fused Phenanthrolines.

Cristina Maria Al Matarneh, Roxana Maria Amarandi, Anda Mihaela Craciun, Ionel I Mangalagiu, Gheorghita Zbancioc, Ramona Danac

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina Maria Al MatarnehFaculty of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I, Iasi 700506, Romania.
Roxana Maria AmarandiFaculty of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I, Iasi 700506, Romania.
Anda Mihaela CraciunFaculty of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I, Iasi 700506, Romania.
Ionel I MangalagiuFaculty of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I, Iasi 700506, Romania.
Gheorghita ZbanciocFaculty of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I, Iasi 700506, Romania.
Ramona DanacFaculty of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I, Iasi 700506, Romania.ORCID 0000-0003-4370-5353

Funding

Ministerul Educației și Cercetării Științifice 34PFE/19.10.2018Ministerul Educației și Cercetării Științifice PN-III-P1-1.1-TE-2016-1205
6 · The paper itself

Abstract

Three series of fused pyrrolophenanthroline derivatives were designed as analogues of phenstatin and synthesized in two steps starting with 1,7-phenanthroline, 4,7-phenanthroline and 1,10-phenanthroline, respectively. Two (Compounds

Indexed as

Chemistry Techniques, SyntheticDrug DesignModels, MolecularAntineoplastic AgentsCell Line, TumorCell ProliferationHumansMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructurePhenanthrolinesStructure-Activity RelationshipAntineoplastic AgentsPhenanthrolines3 + 2 cycloadditionanticancerphenanthrolinesphenstatintubulin docking

Identifiers

PMID31991806
PMCPMC7036904

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.