Evidence map›Paper›PMID 31991791›Full record

ArticleCells2020

Dynamic Changes in Function and Proteomic Composition of Extracellular Vesicles from Hepatic Stellate Cells during Cellular Activation.

Xinlei Li, Ruju Chen, Sherri Kemper, David R Brigstock

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xinlei LiCenter for Clinical and Translational Research, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205, USA.
Ruju ChenCenter for Clinical and Translational Research, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205, USA.
Sherri KemperCenter for Clinical and Translational Research, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205, USA.
David R BrigstockCenter for Clinical and Translational Research, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205, USA.
Nationwide Children's Hospital · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Hepatocyte Exosomes for Therapy of Ethanol-Induced Liver InjuryR21AA025974 · NIAAA · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BRIGSTOCK, DAVID R · 2017 to 2018
$395k
Exosome platforms for assessment and therapy of chronic liver diseaseR21AA023626 · NIAAA · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BRIGSTOCK, DAVID R · 2015 to 2016
$392k
NCI NIH HHS P30 CA016058NIAAA NIH HHS R21 AA023626NIAAA NIH HHS R21 AA025974NIH HHS R21 AA023626NIH HHS R21 AA025974
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell LineCollagenCollagen Type ICollagen Type I, alpha 1 ChainConnective Tissue Growth FactorExtracellular MatrixExtracellular VesiclesGene Expression RegulationGene OntologyHepatic Stellate CellsHistonesHumansKeratinsLiver CirrhosisMaleCCN2 protein, mouseCollagenCollagen Type ICollagen Type I, alpha 1 ChainConnective Tissue Growth FactorHistonesKeratinsProteasome Endopeptidase ComplexProteomeexosomeextracellular vesiclehepatic fibrosishepatic stellate celllivermicrovesicle

Identifiers

PMID31991791
PMCPMC7072607
OpenAlexW3001640094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.