Evidence map›Paper›PMID 31991788›Full record

ArticleInternational journal of molecular sciences2020

Competitive Binding of Magnesium to Calcium Binding Sites Reciprocally Regulates Transamidase and GTP Hydrolysis Activity of Transglutaminase 2.

Eui Man Jeong, Ki Baek Lee, Gi Eob Kim, Chang Min Kim, Jin-Haeng Lee, Hyo-Jun Kim, Ji-Woong Shin, Mee-Ae Kwon, Hyun Ho Park, In-Gyu Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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  10. The Role of Transglutaminase 2 in Cancer: An Update.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Eui Man JeongDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.
Ki Baek LeeDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.
Gi Eob KimCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Chang Min KimCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Jin-Haeng LeeDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.
Hyo-Jun KimDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.
Ji-Woong ShinDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.
Mee-Ae KwonDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.
Hyun Ho ParkCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
In-Gyu KimDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.
Seoul National University · KRChung-Ang University · KR

Funding

Korea Healthcare Technology R&D Project, Ministry of Health and Welfare, Republic of Korea HI18C2396National Research Foundation of Korea NRF-2017M3A9B4061890National Research Foundation of Korea NRF-2017M3A9D8062960National Research Foundation of Korea NRF-2017R1D1A1B03035059National Research Foundation of Korea NRF-2018R1A2B3008541
6 · The paper itself

Abstract

Transglutaminase 2 (TG2) is a Ca

Indexed as

Binding SitesAmino Acid SequenceAminoacyltransferasesBinding, CompetitiveCalciumEnzyme ActivationGTP-Binding ProteinsGuanosine TriphosphateHumansHydrolysisMagnesiumModels, BiologicalMolecular ConformationProtein BindingProtein Glutamine gamma Glutamyltransferase 2Structure-Activity RelationshipAminoacyltransferasesCalciumGTP-Binding ProteinsGuanosine TriphosphateMagnesiumProtein Glutamine gamma Glutamyltransferase 2transamidasesTransglutaminasescalciummagnesiumtransglutaminase 2X-ray crystallography

Identifiers

PMID31991788
PMCPMC7037829
OpenAlexW3001828463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.