Comparative Study of the Effect of 5,6-Dihydroergosterol and 3-

Ye Seul Park, Hye Jin Moon, Kwang Hyun Ahn, Tae Hoon Lee, Hakwon Kim

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 53% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

Structure and Biological Activity of Ergostane-Type Steroids from Fungi.Molecules (Basel, Switzerland) · 2022
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ye Seul ParkDepartment of Applied Chemistry and Global Center for Pharmaceutical Ingredient Materials, Kyung Hee Uinveristy, Yongin-si, Gyeonggi-do17104, Korea.

Hye Jin MoonDepartment of Applied Chemistry and Global Center for Pharmaceutical Ingredient Materials, Kyung Hee Uinveristy, Yongin-si, Gyeonggi-do17104, Korea.

Kwang Hyun AhnDepartment of Applied Chemistry and Global Center for Pharmaceutical Ingredient Materials, Kyung Hee Uinveristy, Yongin-si, Gyeonggi-do17104, Korea.

Tae Hoon LeeDepartment of Applied Chemistry and Global Center for Pharmaceutical Ingredient Materials, Kyung Hee Uinveristy, Yongin-si, Gyeonggi-do17104, Korea.

Hakwon KimDepartment of Applied Chemistry and Global Center for Pharmaceutical Ingredient Materials, Kyung Hee Uinveristy, Yongin-si, Gyeonggi-do17104, Korea.

Kyung Hee University · KR

Funding

Gyeonggi province GRRC-KyungHee-2018(B01)

6 · The paper itself

Abstract

5,6-Dihydroergosterol-glucose is an organic synthetic derivative of spinasterol-glucose, which has potent anti-inflammatory activity. We previously synthesized alpha and beta anomers of DHE-glycosides and compared their inhibitory activity on CCL17 and CCL22 mRNA expression induced by TNF-α/IFN-γ in activated HaCaTs. Recently, we synthesized a new type of DHE-glycosides, 3-

Indexed as

Cells, CulturedChemokinesCytokinesErgosterolGene Expression RegulationGlycosylationHumansHydrolysisKeratinocytesModels, MolecularMolecular ConformationMolecular StructureChemokinesCytokinesErgosterol3-epi-5,6-dihydroergosterol glycosideanti-inflammationCCL17/TARCCCL22/MDCchronic dermatitis treatment

Identifiers

PMID31991764

DOI10.3390/molecules25030522

PMCPMC7036979

OpenAlexW3001798469

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.