Evidence map›Paper›PMID 31991751›Full record

ArticleBiomolecules2020

Asiatic Acid, Extracted from

Yen-Tze Liu, Yi-Ching Chuang, Yu-Sheng Lo, Chia-Chieh Lin, Yi-Ting Hsi, Ming-Ju Hsieh, Mu-Kuan Chen

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Can Asiatic Acid fromCancers · 2024
    Review
  8. Increased Expression of KNeurochemical research · 2024
    Article
  9. Uncovering the Anti-Angiogenic Mechanisms ofMolecules (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma.International journal of molecular sciences · 2022
    Review
  17. Article
  18. Article
  19. Dehydrocrenatidine extracted fromOncology reports · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yen-Tze LiuInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Yi-Ching ChuangOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Yu-Sheng LoOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Chia-Chieh LinOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Yi-Ting HsiOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Ming-Ju HsiehInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Mu-Kuan ChenDepartment of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua 500, Taiwan.
Changhua Christian Hospital · TWMingDao University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is an important issue in Asia because of its unique geographical and ethnic distribution. Cisplatin-based regimens are commonly the first-line used chemotherapy, but resistance and toxicities remain a problem. Therefore, the use of anticancer agents derived from natural products may be a solution. Asiatic acid (AA), extracted from

Indexed as

ApoptosisCell Line, TumorCell ProliferationCell SurvivalCentellaCisplatinDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticHumansNasopharyngeal Carcinomap38 Mitogen-Activated Protein KinasesPentacyclic TriterpenesPhosphorylationPlant ExtractsSignal TransductionTriterpenesasiatic acidCentella asiatica extractCisplatinp38 Mitogen-Activated Protein KinasesPentacyclic TriterpenesPlant ExtractsTriterpenesapoptosisAsiatic acidcisplatin resistanceMAPK pathwaynasopharyngeal cancer

Identifiers

PMID31991751
PMCPMC7072674
OpenAlexW3000854008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.