ArticleMarine drugs2020
Metabolomic Insights into Marine Phytoplankton Diversity.
Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Marine Microalgal Genes: Unlocking a New Era of Sustainable High Value PUFA Production for Neuroprotective Applications.Cell biochemistry and biophysics · 2026Review
- Effect of cellular nutrient economy on the evolution of genome size in phytoplankton.Science advances · 2026Article
- These Boots Are Made for Walking: Sex-Specific Physiological and Metabolomic Strategies Reflect Male-Skewed Vulnerability to Ocean Warming in a Keystone Amphipod.Global change biology · 2026Article
- Characterization of phytoplankton-excreted metabolites mediating carbon flux through the surface ocean.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Drought preceding rain events drives shifts in phytoplankton composition and metabolome in Lake Aydat (France) revealing molecular strategies.FEMS microbiology ecology · 2026Article
- From nets to networks: tools for deciphering phytoplankton metabolic interactions within communities and their global significance.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Evaluation of Developmental Toxicity and Oxidative Stress Caused by Zinc Oxide Nanoparticles in Zebra Fish Embryos/ Larvae.Applied biochemistry and biotechnology · 2024Article
- On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral Metabolome.Metabolites · 2023Article
- Bacterial transcriptional response to labile exometabolites from photosynthetic picoeukaryote Micromonas commoda.ISME communications · 2023Article
- Metabolomics of Chlorophylls and Carotenoids: Analytical Methods and Metabolome-Based Studies.Antioxidants (Basel, Switzerland) · 2021Review
- Toxicity of Naphthenic Acids on the Chlorophyll Fluorescence Parameters and Antioxidant Enzyme Activity ofAntioxidants (Basel, Switzerland) · 2021Article
- A unique approach to monitor stress in coral exposed to emerging pollutants.Scientific reports · 2020Article
- Marine Microbial Diversity as a Source of Bioactive Natural Products.Marine drugs · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The democratization of sequencing technologies fostered a leap in our knowledge of the diversity of marine phytoplanktonic microalgae, revealing many previously unknown species and lineages. The evolutionary history of the diversification of microalgae can be inferred from the analysis of their genome sequences. However, the link between the DNA sequence and the associated phenotype is notoriously difficult to assess, all the more so for marine phytoplanktonic microalgae for which the lab culture and, thus, biological experimentation is very tedious. Here, we explore the potential of a high-throughput untargeted metabolomic approach to explore the phenotypic-genotypic gap in 12 marine microalgae encompassing 1.2 billion years of evolution. We identified species- and lineage-specific metabolites. We also provide evidence of a very good correlation between the molecular divergence, inferred from the DNA sequences, and the metabolomic divergence, inferred from the complete metabolomic profiles. These results provide novel insights into the potential of chemotaxonomy in marine phytoplankton and support the hypothesis of a metabolomic clock, suggesting that DNA and metabolomic profiles co-evolve.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.