Evidence map›Paper›PMID 31991713›Full record

ReviewAnimals : an open access journal from MDPI2020

Platelet Function and Therapeutic Applications in Dogs: Current Status and Future Prospects.

Laura Cortese, Pete W Christopherson, Alessandra Pelagalli

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Association between patient signalment and platelet function parameters in cats.The Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Article
  3. Optimization of conditions related to Chrono-log platelet aggregation in feline whole blood.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2025
    Article
  4. Article
  5. P2YInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. One Health: Animal Models of Heritable Human Bleeding Diseases.Animals : an open access journal from MDPI · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Laura CorteseDepartment of Veterinary Medicine and Animal Productions, Division of Internal Medicine, University of Naples Federico II, Via Delpino, 1, 80137 Naples, Italy.
Pete W ChristophersonDepartment of Pathobiology, Auburn University College of Veterinary Medicine, Auburn University, 36849 Alabama, USA.
Alessandra PelagalliDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", 80131 Naples, Italy.
Auburn University · USInstitute of Biostructure and Bioimaging · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significant progress has been made in the functional characterization of canine platelets in the last two decades. The role of canine platelets in hemostasis includes their adhesion to the subendothelium, activation, and aggregation, leading to primary clot formation at the site of injury. Studies on canine platelet function and advancements in laboratory testing have improved the diagnosis and understanding of platelet-related disorders as well as the knowledge of the mechanisms behind these diseases. This review focuses on the most recent discoveries in canine platelet structure, function, and disorders; and discusses the efficacy of various tests in the diagnosis of platelet-related disorders. With the relatively recent discovery of angiogenetic and reparative effects of growth factors found in platelets, this review also summarizes the use of canine platelet-rich plasma (PRP) alone or in association with stem cells in regenerative therapy. The characterization of proteomic and lipidomic profiles and development of platelet gene therapy in veterinary species are areas of future study with potential for major therapeutic benefits.

Indexed as

dogphysiologyplateletsregenerative medicinetherapy

Identifiers

PMID31991713
PMCPMC7071006
OpenAlexW3002380266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.