Evidence map›Paper›PMID 31991614›Full record

ReviewCells2020

Prognosis, Biology, and Targeting of

Erin Flynt, Kamlesh Bisht, Vinidhra Sridharan, María Ortiz, Fadi Towfic, Anjan Thakurta

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. International Myeloma Society/International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Guideline
  2. Pooled it
  3. Article
  4. iScience · 2026
    Article
  5. Article
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  7. Article
  8. Article
  9. Article
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  11. [Value of gene mutation in the prognosis and treatment of multiple myeloma].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erin FlyntCelgene Corporation, Summit, NJ 07901, USA.
Kamlesh BishtCelgene Corporation, Summit, NJ 07901, USA.
Vinidhra SridharanCelgene Corporation, Summit, NJ 07901, USA.
María OrtizCelgene Corporation, Celgene Institute for Translational Research Europe, Sevilla 41092, Spain.
Fadi TowficCelgene Corporation, San Diego, CA 92121, USA.
Anjan ThakurtaCelgene Corporation, Summit, NJ 07901, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is the second most common hematological cancer and is characterized by genetic features including translocations, chromosomal copy number aberrations, and mutations in key oncogene and tumor suppressor genes. Dysregulation of the tumor suppressor

Indexed as

AllelesAneuploidyAnimalsCell Cycle CheckpointsChromosome DeletionDNA RepairDrug DevelopmentGene Expression Regulation, NeoplasticGenomic InstabilityGenomicsHumansMultiple MyelomaRisk FactorsTumor Suppressor Protein p53TP53 protein, humanTumor Suppressor Protein p53del17pgenomicshigh-riskmyelomaP53

Identifiers

PMID31991614
PMCPMC7072230
OpenAlexW3000961023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.