Evidence map›Paper›PMID 31991605›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Study of 1D and 2D Carbon Nanomaterial in Alginate Films.

Beatriz Salesa, Mar Llorens-Gámez, Ángel Serrano-Aroca

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Review
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  7. Article
  8. Alginate: Enhancement Strategies for Advanced Applications.International journal of molecular sciences · 2022
    Review
  9. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Beatriz SalesaBiomaterials and Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, c/Guillem de Castro 94, 46001 Valencia, Spain.
Mar Llorens-GámezInstitute for Research and Innovation in Bioengineering, Universitat Politècnica de València, Camí de Vera s/n, 46022 Valencia, Spain.
Ángel Serrano-ArocaBiomaterials and Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, c/Guillem de Castro 94, 46001 Valencia, Spain.
Valencia Catholic University Saint Vincent Martyr · ESUniversitat Politècnica de València · ES

Funding

FUNDACIÓN UNIVERSIDAD CATÓLICA DE VALENCIA SAN VICENTE MÁRTIR 2019-231-003UCV
6 · The paper itself

Abstract

Alginate-based materials hold great promise in bioengineering applications such as skin wound healing and scaffolds for tissue engineering. Nevertheless, cell adhesion of mammalian cells on these hydrophilic materials is very poor. In cases such as polycaprolactone, poly(hydroxy-3-butyrate-co-3-valerate) and gelatin, the incorporation of hydrophobic carbon nanofibers (CNFs) and hydrophilic graphene oxide (GO) has shown significant improvement of cell adhesion and proliferation. The incorporation of these carbon nanomaterials (CNMs) into alginate films can enhance their mechanical performance, wettability, water diffusion and antibacterial properties. Herein, we report the effect of adding these CNMs into alginate films on cell adhesion for the first time. Thus, the results of this study showed that these nanocomposites are non-cytotoxic in human keratinocyte HaCaT cells. Nevertheless, contrary to what has been reported for other polymers, cell adhesion on these advanced alginate-based composites was not improved. Therefore, both types of composite films possess similar biological behavior, in terms of cell adhesion and non-cytotoxicity, and enhanced physical and antibacterial properties in comparison to neat alginate for potential biomedical and bioengineering applications.

Indexed as

calcium alginatecarbon nanofiberscell adhesioncytotoxicityfilmsgraphene oxidehuman keratinocyte HaCaT cells

Identifiers

PMID31991605
PMCPMC7074849
OpenAlexW3002097739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.