ArticleJournal of the Chinese Medical Association : JCMA2020
Adenovirus infection and subsequent risk of Kawasaki disease: A population-based cohort study.
Article in Journal of the Chinese Medical Association : JCMA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Potential Mechanisms and Hypotheses for Pathogenic Microorganisms Triggering Kawasaki Disease.Clinical reviews in allergy & immunology · 2025Review
- Add in a virus: four cases of severe Kawasaki disease and concurrent adenovirus infection.BMC pediatrics · 2025Article
- Bacterial-like inflammatory response in children with adenovirus leads to inappropriate antibiotic use: a multicenter cohort study.Infection · 2025Article
- Impact of a Concurrent Respiratory Virus Infection on the Clinical Presentation and Response to Initial Treatment of Kawasaki Disease: A Single-Center Observational Study.Journal of clinical medicine · 2025Article
- Editorial: Reviews in microbial pathogenesis.Frontiers in microbiology · 2025Article
- Risks of Kawasaki disease and multisystem inflammatory syndrome in pediatric patients with COVID-19 infection: A TriNetX based cohort study.Journal of the Chinese Medical Association : JCMA · 2024Article
- Kawasaki Disease and Respiratory Viruses: Ecological Spatiotemporal Analysis.JMIR public health and surveillance · 2024Article
- Calculating the fraction of Kawasaki disease potentially attributable to seasonal pathogens: a time series analysis.EClinicalMedicine · 2023Article
- Emerging evidence of microbial infection in causing systematic immune vasculitis in Kawasaki disease.Frontiers in microbiology · 2023Review
- Impact of Kawasaki disease on juvenile idiopathic arthritis in real-world patients: A population-based cohort study.Frontiers in immunology · 2022Article
- Nonenteric Adenoviruses Associated with Gastroenteritis in Hospitalized Children.Microbiology spectrum · 2021Article
- Clinical characteristics of Kawasaki disease and concurrent pathogens during isolation in COVID-19 pandemic.World journal of pediatrics : WJP · 2021Article
- Another compelling evidence suggesting infectious diseases as the cause of Kawasaki disease?Journal of the Chinese Medical Association : JCMA · 2020Article
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Authors and funding
10 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between adenovirus infection and Kawasaki disease (KD) is unclear. The purpose of this study was to determine the relationship between adenovirus infection and KD using a cohort study in Taiwan.
methodsWe used Taiwan National Health Insurance data (from 2000 to 2008) to conduct a population-based cohort study, analyzing children that was under 18 years of age. In total, 5280 children had adenovirus infection, and 5280 children without adenovirus infection were matched and followed up. Subsequent KD was the major outcome event. The Cox proportional hazards model was used to estimate the hazard ratio (HR) with 95% confidence intervals (CIs) of developing KD associated with adenovirus infection.
resultsThere was a significantly higher cumulative incidence of KD in the adenovirus-infected cohort than that in the control cohort (log-rank test, p < 0.001). In the adenovirus-infected cohort, overall incidence of KD was 5.29 times higher than that of the control cohort (adjusted HR 5.29, 95% CI: 2.48-11.3). Increased KD risk was associated with previous adenovirus infection in children aged 3-5 years, in female patients, in those with a low urbanization level, and in those with allergies.
conclusionAn association between previous adenovirus infection and KD was identified in Taiwanese children, but other potential risk factors were not fully analyzed. The relationship between infection and KD requires further study.
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