Evidence map›Paper›PMID 31990563›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2020

Specific Disruption of Established

Kristin N Kovach, Derek Fleming, Marilyn J Wells, Kendra P Rumbaugh, Vernita Diane Gordon

Open access · greenAbstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

  1. Extracellular matrix chemistry tunes bacterial biofilm metabolism and optimizes fitness.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Biofilm · 2025
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  6. Review
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  11. An apparent lack of synergy between degradative enzymes againstbioRxiv : the preprint server for biology · 2023
    Article
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  13. Review
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  15. Article
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  18. Treatment ofFrontiers in microbiology · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kristin N KovachDepartment of Physics and Center for Nonlinear Dynamics , The University of Texas at Austin , Austin , Texas 78712 , United States.
Derek FlemingDepartment of Surgery , Texas Tech University Health Sciences Center , Lubbock , Texas 79430 , United States.
Marilyn J WellsDepartment of Physics and Center for Nonlinear Dynamics , The University of Texas at Austin , Austin , Texas 78712 , United States.
Kendra P RumbaughDepartment of Surgery , Texas Tech University Health Sciences Center , Lubbock , Texas 79430 , United States.
Vernita Diane GordonDepartment of Physics and Center for Nonlinear Dynamics , The University of Texas at Austin , Austin , Texas 78712 , United States.ORCID 0000-0002-5989-9378
The University of Texas at Austin · USTexas Tech University · US

Funding

Assessing the roles of biofilm structure and mechanics in pathogenic, persistent infectionsR01AI121500 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI GORDON, VERNITA DIANE · 2017 to 2020
$1.5M
Utilizing Glycoside Hydrolases to Degrade Biofilms in WoundsR21AI137462 · NIAID · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI RUMBAUGH, KENDRA P · 2019 to 2020
$286k
NIAID NIH HHS R01 AI121500NIAID NIH HHS R21 AI137462
6 · The paper itself

Abstract

Biofilms are communities of bacteria embedded in a polymeric matrix which are found in infections and in environments outside the body. Breaking down the matrix renders biofilms more susceptible to physical disruption and to treatments such as antibiotics. Different species of bacteria, and different strains within the same species, produce different types of matrix polymers. This suggests that targeting specific polymers for disruption may be more effective than nonspecific approaches to disrupting biofilm matrixes. In this study, we treated

Indexed as

PolymersPseudomonas aeruginosaAnimalsAnti-Bacterial AgentsBiofilmsMiceAnti-Bacterial AgentsPolymers

Identifiers

PMID31990563
PMCPMC7063831
OpenAlexW3003933287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.