Evidence map›Paper›PMID 31990112›Full record

ArticleNMR in biomedicine2021

In vivo Glx and Glu measurements from GABA-edited MRS at 3 T.

Tiffany Bell, Elodie S Boudes, Rachelle S Loo, Gareth J Barker, David J Lythgoe, Richard A E Edden, R Marc Lebel, Martin Wilson, Ashley D Harris

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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  8. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Tiffany BellDepartment of Radiology, University of Calgary, Calgary, Canada.ORCID 0000-0002-9591-706X
Elodie S BoudesDepartment of Radiology, University of Calgary, Calgary, Canada.
Rachelle S LooDepartment of Radiology, University of Calgary, Calgary, Canada.
Gareth J BarkerDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
David J LythgoeDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Richard A E EddenRussel H Morgan Department of Radiology, The Johns Hopkins School of Medicine, Baltimore, USA.
R Marc LebelGeneral Electric Healthcare, Calgary, AB, Canada.
Martin WilsonCentre for Human Brain Health and School of Psychology, University of Birmingham, Birmingham, UK.
Ashley D HarrisDepartment of Radiology, University of Calgary, Calgary, Canada.
University of Calgary · CAKing's College London · GBGeneral Electric (Canada) · CAKennedy Krieger Institute · USUniversity of Birmingham · GB

Funding

TR&D 4: Algorithms for functional and anatomical brain analysisP41EB015909 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VAN ZIJL, PETER CM · 2012 to 2020
$13.1M
Universal GABA-edited MRS at 3TR01EB016089 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Richard Anthony Edward Edden · 2013 to 2026
$5.4M
NIBIB NIH HHS P41 EB015909NIBIB NIH HHS R01 EB016089
6 · The paper itself

Abstract

In vivo quantification of glutamate (Glu) and γ-aminobutyric acid (GABA) using MRS is often achieved using two separate sequences: a short-echo point resolved spectroscopy (PRESS) acquisition for Glu and a Mescher-Garwood PRESS (MEGA-PRESS) acquisition for GABA. The purpose of this study was to examine the agreement of Glu and Glx (the combined signal of glutamate + glutamine) quantified from two different GABA-edited MEGA-PRESS acquisitions (GABA plus macromolecules, GABA+, T

Indexed as

Magnetic Resonance SpectroscopyAdolescentAdultConfidence Intervalsgamma-Aminobutyric AcidGlutamic AcidGlutamineGyrus CinguliHumansMaleSensorimotor CortexYoung Adultgamma-Aminobutyric AcidGlutamic AcidGlutamineglutamateGlxMEGA-PRESSPRESSGABA-edited MRS

Identifiers

PMID31990112
PMCPMC7384936
OpenAlexW3003953083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.