Evidence map›Paper›PMID 31989919›Full record

ArticleThe American journal of tropical medicine and hygiene2020

Decline in Total Serum IgE and Soluble CD30 in the Context of Soil-Transmitted Helminth Decline in Bolivia.

Chiara Della Bella, Michele Spinicci, David Rojo, Alessia Grassi, Herlan Gamboa, Marisa Benagiano, Roberto Torrez, Simona Tapinassi, Simona Gabrielli, Gabriella Cancrini and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 4 countries.

Chiara Della BellaDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
Michele SpinicciDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
David RojoEscuela de Salud del Chaco Tekove Katu, Gutierrez, Plurinational State of Bolivia.
Alessia GrassiDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
Herlan GamboaFacultad Integral del Chaco, Universidad Autónoma Gabriel René Moreno, Camiri, Plurinational State of Bolivia.
Marisa BenagianoDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
Roberto TorrezServicio Departamental de Salud (SEDES) de Santa Cruz, Santa Cruz, Plurinational State of Bolivia.
Simona TapinassiDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
Simona GabrielliDipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma Sapienza, Roma, Italy.
Gabriella CancriniDipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma Sapienza, Roma, Italy.
Fabio MacchioniDipartimento di Scienze Veterinarie, Università degli Studi di Pisa, Pisa, Italy.
Heba AlnwaisriDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
Annalisa AzzurriDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
Joaquín MonasterioServicio Departamental de Salud (SEDES) de Santa Cruz, Santa Cruz, Plurinational State of Bolivia.
Antonio MontresorDepartment of Control of Neglected Tropical Diseases (NTD), World Health Organization, Geneva, Switzerland.
Piero OlliaroNuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
Mario Milco D'EliosDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
Alessandro BartoloniDipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
University of Florence · ITSapienza University of Rome · ITGabriel René Moreno Autonomous University · BONuffield Health · GBUniversidad Privada Del Chaco · BOUniversity of Pisa · ITWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

In the Bolivian Chaco, recent surveys documented a dramatic decrease in the prevalence of soil-transmitted helminth (STH) infections as compared with the 1980s after thirty years of preventive chemotherapy (PC). Concomitant immunological rearrangements are expected. Because nematode infections are associated with increased levels of circulating IgE and glycoprotein CD30 soluble form (sCD30), this study aims to evaluate changes in serological markers of T helper (Th)2-cells activity between 1987 (high STH prevalence) and 2013 (low STH prevalence) in rural communities in the Bolivian Chaco area. We collected 151 sera during two different surveys in 1987 (

Indexed as

AdultAntibodies, HelminthBoliviaFemaleHelminthiasisHumansImmunoglobulin EKi-1 AntigenMaleSoilAntibodies, HelminthImmunoglobulin EKi-1 AntigenSoil

Identifiers

PMID31989919
PMCPMC7124912
OpenAlexW3003782722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.