Evidence map›Paper›PMID 31989854›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2020

Temporal Expression and Cellular Localization of PAPPA2 in the Developing Kidney of Rat.

Vikash Kumar, Chun Yang, Allen W Cowley

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vikash KumarDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Chun YangDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Allen W CowleyDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Medical College of Wisconsin · US

Funding

Single-Cell Epigenomics, Transcriptomics, and Bioinformatics CoreP50DK096373 · NIDDK · UNIVERSITY OF VIRGINIA · PI Silvia Medrano · 2012 to 2026
$13.8M
NIDDK NIH HHS P50 DK096373
6 · The paper itself

Abstract

PAPPA2 is a metalloproteinase which cleaves insulin-like growth factor binding protein (IGFBP)-3 and IGFBP-5, and its role in pregnancy and postnatal growth is primarily studied. Using exclusion mapping, we reported a subcongenic (26-P) rat where a 0.71-Mbp region containing the pregnancy-associated plasma protein a2 (

Indexed as

AnimalsAnimals, NewbornDisease Models, AnimalFemaleGene ExpressionInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor Binding Protein 5Ion TransportKidneyMalePregnancyPregnancy-Associated Plasma Protein-APregnancy ComplicationsRatsRats, Inbred BNRats, Inbred DahlInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor Binding Protein 5Pregnancy-Associated Plasma Protein-ARNA, MessengerSodium-Potassium-Chloride Symportersblood pressurecongenichypertensionkidney injurynephron number

Identifiers

PMID31989854
PMCPMC7045303
OpenAlexW3003212804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.