Evidence map›Paper›PMID 31989813›Full record

ArticleAnalytical chemistry2020

Charge Detection Mass Spectrometry Measurements of Exosomes and other Extracellular Particles Enriched from Bovine Milk.

Brooke A Brown, Xuyao Zeng, Aaron R Todd, Lauren F Barnes, Jonathan M A Winstone, Jonathan C Trinidad, Milos V Novotny, Martin F Jarrold, David E Clemmer

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Article
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  7. Review
  8. To 200,000ACS central science · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Exosome Mediated Cell-Cell Crosstalk in Tissue Injury and Repair.Results and problems in cell differentiation · 2024
    Review
  13. Article
  14. Article
  15. Dissecting the structural heterogeneity of proteins by native mass spectrometry.Protein science : a publication of the Protein Society · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Brooke A BrownDepartment of Chemistry , Indiana University , Bloomington , Indiana 47505 , United States.
Xuyao ZengDepartment of Chemistry , Indiana University , Bloomington , Indiana 47505 , United States.
Aaron R ToddDepartment of Chemistry , Indiana University , Bloomington , Indiana 47505 , United States.
Lauren F BarnesDepartment of Chemistry , Indiana University , Bloomington , Indiana 47505 , United States.
Jonathan M A WinstoneDepartment of Chemistry , Indiana University , Bloomington , Indiana 47505 , United States.
Jonathan C TrinidadDepartment of Chemistry , Indiana University , Bloomington , Indiana 47505 , United States.
Milos V NovotnyDepartment of Chemistry , Indiana University , Bloomington , Indiana 47505 , United States.ORCID 0000-0001-5530-7059
Martin F JarroldDepartment of Chemistry , Indiana University , Bloomington , Indiana 47505 , United States.ORCID 0000-0001-7084-176X
David E ClemmerDepartment of Chemistry , Indiana University , Bloomington , Indiana 47505 , United States.ORCID 0000-0003-4039-1360
Indiana University Bloomington · US

Funding

Graduate Training Program in Quantitative and Chemical Biology at Indiana University BloomingtonT32GM131994 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI JARED C LEWIS · 2019 to 2026
$2.4M
Developing High-Resolution Ion Mobility Spectrometry-Charge Detection-Mass Spectrometry for Rapid Analysis in the Megadalton to Gigadalton RegimeR01GM131100 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CLEMMER, DAVID E., JARROLD, MARTIN F · 2019 to 2022
$2.1M
Graduate Program in Quantitative and Chemical Biology at Indiana University BloomT32GM109825 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI GIEDROC, DAVID P. · 2014 to 2018
$926k
NIGMS NIH HHS R01 GM131100NIGMS NIH HHS T32 GM109825NIGMS NIH HHS T32 GM131994
6 · The paper itself

Abstract

The masses of particles in a bovine milk extracellular vesicle (EV) preparation enriched for exosomes were directly determined for the first time by charge detection mass spectrometry (CDMS). In CDMS, both the mass-to-charge ratio (

Indexed as

AnimalsCattleChromatography, LiquidExosomesMass SpectrometryMilkProteomics

Identifiers

PMID31989813
PMCPMC7236431
OpenAlexW3003262476

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.