Evidence map›Paper›PMID 31989777›Full record

ArticleThoracic cancer2020

Novel ProCore 25-gauge needle for endobronchial ultrasound-guided transbronchial needle aspiration reduces the puncture time and frequency, with comparable diagnostic rate for mediastinal and hilar lymphadenopathy.

Li Yang, Ye Gu, Hai Wang, Dongmei Yu, Haiping Zhang, Hao Wang

Abstract read
In one paragraph

Article in Thoracic cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Transbronchial needle core biopsyEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Evolution of transbronchial needle aspiration needles: Over the last half century.Chinese medical journal pulmonary and critical care medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Li YangEndoscopy Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Ye GuEndoscopy Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Hai WangEndoscopy Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Dongmei YuEndoscopy Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Haiping ZhangDepartment of Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Hao WangEndoscopy Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.ORCID 0000-0003-2012-3684

Funding

China National Key Research and Development Plan Project 2017YFC0113501Nursing Intervention Project of Shanghai Pulmonary Hospital HL201714Shanghai Municipal Health Committee Special Project for Clinical Research 20194Y0193the Interventional Pulmonary Key Laboratory of Zhejiang Province 2019E10014
6 · The paper itself

Abstract

backgroundThe ProCore 25-gauge needle is a novel specifically designed puncture needle for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), which may improve the puncture efficiency of the procedure while ensuring the diagnostic rate. The aim of the present study was to evaluate the diagnostic accuracy, mRNA yield, and complication rate of 25-gauge needles compared to those of 22-gauge needles in the evaluation of mediastinal and hilar lymphadenopathy.

methodsA total of 39 patients undergoing EBUS-TBNA at our institution were evaluated. All the procedures were performed by an experienced endoscopist formally trained in interventional pulmonology. Both the traditional 22-gauge and ProCore 25-gauge needles were used at each lymph node station. For all specimens obtained via EBUS-TBNA, 50 μL was used to extract mRNA and detect the RNA concentration, whereas the other part was sent to the pathological evaluation. χ

resultsA total of 88 lymph nodes were punctured by the two needles separately. The diagnostic accuracy for each puncture between the two needles did not show any significant difference (P > 0.05). No serious procedure-related complications were reported. In addition, the mRNA concentration did not differ between the two types of needles (P > 0.05).

conclusionThe ProCore 25-gauge needle gained a similar diagnostic yield with less puncture time and frequency compared with the 22-gauge needle.

Indexed as

AdultAgedBronchoscopyEndoscopic Ultrasound-Guided Fine Needle AspirationFemaleFollow-Up StudiesHumansImage-Guided BiopsyLymphadenopathyMaleMediastinumMiddle AgedPrognosisPuncturesEndobronchial ultrasoundhilar lymphadenopathymRNA extractionRNA concentrationtransbronchial needle aspiration

Identifiers

PMID31989777
PMCPMC7049504

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.