Evidence map›Paper›PMID 31989504›Full record

ArticleEnvironmental science and pollution research international2020

Biological variation in kidney injury and kidney function biomarkers among farmers in Lamphun province, Thailand.

Patthawee Mueangkhiao, Penprapa Siviroj, Ratana Sapbamrer, Supakit Khacha-Ananda, Anusorn Lungkaphin, Mathuramat Seesen, Pittaya Jaikwang, Klintean Wunnapuk

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Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Patthawee MueangkhiaoDepartment of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Penprapa SivirojDepartment of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Ratana SapbamrerDepartment of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Supakit Khacha-AnandaDepartment of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Anusorn LungkaphinDepartment of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Mathuramat SeesenDepartment of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Pittaya JaikwangDepartment of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Klintean WunnapukDepartment of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. klintean.w@cmu.ac.th.ORCID http://orcid.org/0000-0003-0770-2657
Chiang Mai University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frequent and long-term exposure to pesticides can induce acute kidney injury and subsequent chronic kidney diseases. In this study, we aimed to investigate the correlation between kidney injury, kidney function biomarkers, and pesticide use in farmers from the Pasang district, Lamphun province, Thailand. A cross-sectional study was performed in 59 farmers occupationally exposed to various types of pesticides. The levels of urinary neutrophil gelatinase-associated lipocalin (uNGAL), serum creatinine (sCr), urinary microalbumin-to-creatinine ratio (ACR), serum cystatin C (sCys-C), estimated glomerular filtration rate (eGFR), and exposure intensity index (EII) were evaluated. Spearman's correlation and a linear regression analysis were carried out to investigate the association between age, pesticide use, EII, kidney injury markers, and kidney function biomarkers. The most common pesticide used in this study area was glyphosate, followed by paraquat and iprodione. Urinary NGAL levels showed a significant correlation with sCys-C levels, EII, and eGFR Cr-Cys. In addition, the sCr levels were associated with glyphosate use (B = 0.08) and EII (B = 0.01). In conclusion, occupation exposure to pesticides is likely to be linked to kidney injury and dysfunction. Pesticide mix status, pesticide application method, equipment repair status, and personal protective equipment (PPE) use are all involved in changes in kidney markers.

Indexed as

Acute-Phase ProteinsLipocalinsBiomarkersCreatinineCross-Sectional StudiesFarmersHumansProto-Oncogene ProteinsThailandAcute-Phase ProteinsBiomarkersCreatinineLipocalinsProto-Oncogene ProteinsCreatinineCystatin CExposure intensity indexKidney injuryNGALPesticide exposure

Identifiers

PMID31989504
OpenAlexW3000974814

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.