ArticlePediatric surgery international2020
Treatment patterns and outcomes for pancreatic tumors in children: an analysis of the National Cancer Database.
Article in Pediatric surgery international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Malignant Solid Pseudopapillary Neoplasm of the Pancreas: An Orthogonal Analysis.Annals of surgical oncology · 2024Pooled it
- Adult pancreatoblastoma: Systematic review of the literature and case report of a young adult patient.World journal of gastrointestinal oncology · 2025Article
- Pediatric pancreatectomy for neoplasms: indications, outcomes, and implementation of minimally invasive surgery in a Ukrainian tertiary center.BMC pediatrics · 2025Article
- Unraveling the landscape of pediatric pancreatic tumors: Insights from Japan.World journal of gastrointestinal oncology · 2025Article
- Nationwide questionnaire survey on pediatric pancreatic tumors in Japan.World journal of gastrointestinal oncology · 2024Article
- Pancreatic masses in children: a single-center experience over two decades.European journal of pediatrics · 2024Article
- Preservation of Pancreatic Function Should Not Be Disregarded When Performing Pancreatectomies for Pancreatoblastoma in Children.Pediatric reports · 2024Review
- Prognostic factors of pancreatic tumors in children and adolescents: a population study based on the surveillance, epidemiology, and end results database.BMC gastroenterology · 2024Article
- Imaging of pediatric pancreas tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper.Pediatric blood & cancer · 2023Article
- Pancreatoblastoma in children: Clinical management and literature review.Translational oncology · 2022Article
- International Society of Paediatric Surgical Oncology (IPSO) Surgical Practice Guidelines.Ecancermedicalscience · 2022Article
- Long-term outcome of pancreatic function following oncological surgery in children: Institutional experience and review of the literature.World journal of clinical cases · 2021Article
- Could the burden of pancreatic cancer originate in childhood?World journal of gastroenterology · 2021Review
- Surgery of pancreas tumors in pediatric and adolescent patients: a single institution experience in South America.Pediatric surgery international · 2021Article
- A retrospective analysis of pancreas operations in children.Translational gastroenterology and hepatology · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePancreatic tumors are rare in children and limited data are available regarding incidence, treatment, and outcomes. We aim to describe patient and tumor characteristics and to report on survival of these diseases.
methodsChildren with pancreatic tumors were queried from the National Cancer Database (2004-2014). The association between treatment and hazard of death was assessed using Kaplan-Meier method and Cox regression model.
resultsWe identified 109 children with pancreatic tumors; 52% were male and median age at diagnosis was 14 years. Tumors were distributed as follows: pseudopapillary neoplasm (30%), endocrine tumors (27%), pancreatoblastoma (16%), pancreatic adenocarcinoma (16%), sarcoma (6%) and neuroblastoma (5%). Seventy-nine patients underwent surgery, of which 76% achieved R0 resection. Most patients (85%) had lymph nodes examined, of which 22% had positive nodes. Five-year overall survival by tumor histology was 95% (pseudopapillary neoplasm), 75% (neuroblastoma), 70% (pancreatoblastoma), 51% (endocrine tumors), 43% (sarcoma), and 34% (adenocarcinoma). On multivariable analysis, surgical resection was the strongest predictor of survival (HR 0.26, 95% CI 0.10-0.68, p < 0.01).
conclusionOverall survival of children with pancreatic tumors is grim, with varying survival rates among different tumors. Surgical resection is associated with improved long-term survival.
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