Evidence map›Paper›PMID 31989224›Full record

ReviewApplied microbiology and biotechnology2020

Progress in research and application development of surface display technology using Bacillus subtilis spores.

Ping Lin, Haibo Yuan, Jieke Du, Kaiquan Liu, Hongling Liu, Tengfei Wang

Abstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Sporulation kinetics ofApplied and environmental microbiology · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Surface display of LukF-PV onFuture microbiology · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Display of Lignin Peroxidase on the Surface of Bacillus subtilis.Applied biochemistry and biotechnology · 2024
    Article
  14. Display of Bacterial Exochitanase onMolecules (Basel, Switzerland) · 2024
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ping LinState Key Laboratory of Biobased Material and Green Papermaking (LBMP), Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China.
Haibo YuanState Key Laboratory of Biobased Material and Green Papermaking (LBMP), Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China.
Jieke DuState Key Laboratory of Biobased Material and Green Papermaking (LBMP), Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China.
Kaiquan LiuState Key Laboratory of Biobased Material and Green Papermaking (LBMP), Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China.
Hongling LiuState Key Laboratory of Biobased Material and Green Papermaking (LBMP), Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China. lhl0538@163.com.
Tengfei WangState Key Laboratory of Biobased Material and Green Papermaking (LBMP), Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China. wangtengfeiSCI@163.com.ORCID http://orcid.org/0000-0003-0735-7259

Funding

A Project of Shandong Province Higher Educational Science and Technology Program A18KA116National Natural Science Foundation of China (CN) 31501413Natural Science Foundation of Shandong Province ZR2017BC072Natural Science Foundation of Shandong Province ZR2019PC060Shandong key project of Research & Development plan 2017GSF221019State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences ZZ20190314Young doctorate Cooperation Fund Project, QiLu University of Technology (Shandong Academy of Sciences) 2017BSHZ021
6 · The paper itself

Abstract

Bacillus subtilis is a widely distributed aerobic Gram-positive species of bacteria. As a tool in the lab, it has the advantages of nonpathogenicity and limited likelihood of becoming drug resistant. It is a probiotic strain that can be directly used in humans and animals. It can be induced to produce spores under nutrient deficiency or other adverse conditions. B. subtilis spores have unique physical, chemical, and biochemical characteristics. Expression of heterologous antigens or proteins on the surface of B. subtilis spores has been successfully performed for over a decade. As an update and supplement to previously published research, this paper reviews the latest research on spore surface display technology using B. subtilis. We have mainly focused on the regulation of spore coat protein expression, display and application of exogenous proteins, and identification of developing research areas of spore surface display technology.

Indexed as

AnimalsBacillus subtilisBacterial ProteinsCell Surface Display TechniquesMiceRecombinant ProteinsResearchSpores, BacterialBacterial ProteinsRecombinant ProteinsBacillus subtilisCoat proteinSporesSurface display

Identifiers

PMID31989224
PMCPMC7223921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.