Evidence map›Paper›PMID 31989034›Full record

ArticleBioengineering & translational medicine2020

Manipulation of the dually thermoresponsive behavior of peptide-based vesicles through modification of collagen-like peptide domains.

Lucas C Dunshee, Millicent O Sullivan, Kristi L Kiick

Abstract read
In one paragraph

Article in Bioengineering & translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A Systematic Review of Tissue Engineering Scaffold in Tendon Bone HealingFrontiers in bioengineering and biotechnology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lucas C DunsheeDepartment of Chemical and Biomolecular Engineering University of Delaware Newark Delaware.ORCID https://orcid.org/0000-0001-6025-5222
Millicent O SullivanDepartment of Chemical and Biomolecular Engineering University of Delaware Newark Delaware.
Kristi L KiickDepartment of Materials Science and Engineering University of Delaware Newark Delaware.

Funding

Collagen-based targeting for improving delivery and efficacy of osteoarthritis drugsR21AR069778 · NIAMS · UNIVERSITY OF DELAWARE · PI KIICK, KRISTI L, PRICE, CHRISTOPHER · 2017 to 2018
$365k
NIAMS NIH HHS R21 AR069778
6 · The paper itself

Abstract

Materials that respond to temporally defined exogenous cues continue to be an active pursuit of research toward on-demand nanoparticle drug delivery applications, and using one or more exogenous temperature stimuli could significantly expand the application of nanoparticle-based drug delivery formulations under both hyperthermal and hypothermal conditions. Previously we have reported the development of a biocompatible and thermoresponsive elastin-

Identifiers

PMID31989034
PMCPMC6971430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.