Evidence map›Paper›PMID 31988903›Full record

ArticleBiomedicine hub

The Effect of Antiretroviral Naïve HIV-1 Infection on the Ability of Natural Killer Cells to Produce IFN-γ upon Exposure to Plasmodium falciparum-Infected Erythrocytes.

Carole Stéphanie Sake, Loveline Ngu, Georgia Ambada, Jean Paul Chedjou, Nadesh Nji, Jules Colince Tchadji, Abel Lissom, Thibau Flaurant Tchouangueu, Larissa Djukouo, Ghislain Njambe and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicine hub. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 4 countries.

Carole Stéphanie SakeLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Loveline NguLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Georgia AmbadaLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Jean Paul ChedjouDepartment of Animal Biology and Physiology, University of Yaoundé I, Yaoundé, Cameroon.
Nadesh NjiLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Jules Colince TchadjiLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Abel LissomLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Thibau Flaurant TchouangueuLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Larissa DjukouoLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Ghislain NjambeLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Rosario GarciaCSCB (Centre de santé catholique de Bikop), Bikop, Cameroon.
Anna GutierrezCSCB (Centre de santé catholique de Bikop), Bikop, Cameroon.
Alain Bopda WaffoDepartment of Biological Sciences, Alabama State University, Montgomery, AL, USA.
Chae Gyu ParkLaboratory of Immunology, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
Wilfried MbachamDepartment of Biochemistry, University of Yaoundé I, Yaoundé, Cameroon.
François-Xavier EtoaDepartment of Microbiology, University of Yaoundé I, Yaoundé, Cameroon.
Godwin W NchindaLaboratory of Vaccinology/Biobanking, CIRCB, Messa Yaounde, Cameroon.
Université de Yaoundé I · CMCentre International De Reference Chantal Biya · CMAlabama State University · USUniversité de Dschang · CMUniversity of Douala · CMYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn sub-Saharan Africa, intense perennial

methodMagnetically sorted NK cells from antiretroviral naïve HIV-1-infected people were tested for their ability to respond to iRBC following in vitro coculture. NK cell IFN-γ production after coculture was measured through multiparametric flow cytometry analysis.

resultsOur data show a significant reduction (

Indexed as

Antiretroviral naïve HIV infectionInfected red blood cellsMalariaNatural killer cells

Identifiers

PMID31988903
PMCPMC6945957
OpenAlexW2606648897

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.