Evidence map›Paper›PMID 31988880›Full record

ArticlePediatric gastroenterology, hepatology & nutrition2020

Impact of Intravenous Omega-3-Enriched Lipid Emulsion on Liver Enzyme and Triglyceride Serum Levels of Children Undergoing Gastrointestinal Surgery.

Meta Herdiana Hanindita, Nur Aisiyah Widjaja, Roedi Irawan, Boerhan Hidayat, Igb Adria Hariastawa

Open access · diamondAbstract read
In one paragraph

Article in Pediatric gastroenterology, hepatology & nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Meta Herdiana HaninditaDepartment of Child Health, Dr. Soetomo Hospital, Medical School, Airlangga University, Surabaya, Indonesia.ORCID https://orcid.org/0000-0001-8914-0007
Nur Aisiyah WidjajaDepartment of Child Health, Dr. Soetomo Hospital, Medical School, Airlangga University, Surabaya, Indonesia.ORCID https://orcid.org/0000-0001-7088-1278
Roedi IrawanDepartment of Child Health, Dr. Soetomo Hospital, Medical School, Airlangga University, Surabaya, Indonesia.ORCID https://orcid.org/0000-0001-5999-4773
Boerhan HidayatDepartment of Child Health, Dr. Soetomo Hospital, Medical School, Airlangga University, Surabaya, Indonesia.ORCID https://orcid.org/0000-0003-3649-1924
Igb Adria HariastawaDepartment of Pediatric Surgery, Dr. Soetomo Hospital, Medical School, Airlangga University, Surabaya, Indonesia.ORCID https://orcid.org/0000-0001-5274-1079
Airlangga University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the impact of omega-3-enriched lipid emulsion (LE) on liver enzyme (aspartate transaminase [AST] and alanine aminotransferase [ALT]) and triglyceride (TG) levels of children undergoing gastrointestinal surgery.

methodsThis experimental randomized controlled group pretest-posttest design study included 14 children who underwent gastrointestinal surgery due to duodenal atresia, jejunal atresia, esophageal atresia, and need for parenteral nutrition for a minimum of 3 days at RSUD Dr. Soetomo Surabaya between August 2018 and January 2019. These children were divided into two groups, those who received standard intravenous LE (medium-chain triglyceride [MCT]/long-chain triglyceride [LCT]) and those who received intravenous omega-3-enriched LE. Differences in AST, ALT, and TG levels were measured before surgery and 3 days after the administration of parenteral nutrition.

resultsLiver enzyme and TG levels in each group did not differ significantly before versus 3 days after surgery. However, TG levels were significantly lower in the omega-3-enriched intravenous LE group (

conclusionThe intravenous omega-3-enriched LE had a better TG-lowering effect than the MCT/LCT intravenous LE in children undergoing gastrointestinal surgery.

Indexed as

Fatty acidsGastrointestinal surgeryOmega-3Parenteral nutrition

Identifiers

PMID31988880
PMCPMC6966215
OpenAlexW3000641159

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.