Evidence map›Paper›PMID 31988469›Full record

ArticleMucosal immunology2020

MicroRNA miR-155 is required for expansion of regulatory T cells to mediate robust pregnancy tolerance in mice.

John E Schjenken, Lachlan M Moldenhauer, Bihong Zhang, Alison S Care, Holly M Groome, Hon-Yeung Chan, Christopher M Hope, Simon C Barry, Sarah A Robertson

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Development and function of FOXP3+ regulators of immune responses.Clinical and experimental immunology · 2023
    Article
  10. Article
  11. Frontiers in immunology · 2023
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Mesenchymal Stem Cell-Secreted TGF-Stem cells international · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

John E Schjenken *The Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia.
Lachlan M Moldenhauer *The Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia.
Bihong ZhangThe Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia.
Alison S CareThe Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia.
Holly M GroomeThe Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia.
Hon-Yeung ChanThe Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia.
Christopher M HopeThe Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia.
Simon C BarryThe Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia.
Sarah A RobertsonThe Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia. sarah.robertson@adelaide.edu.au.ORCID http://orcid.org/0000-0002-9967-0084
The University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune-regulatory microRNA miR-155 is reduced in recurrent miscarriage, suggesting that miR-155 contributes to immune tolerance in pregnancy. Here we show miR-155 is induced in the uterine mucosa and draining lymph nodes (dLN) during the female immune response to male seminal fluid alloantigens. Mice with null mutation in miR-155 (miR-155

Indexed as

Abortion, SpontaneousAnimalsBiomarkersCytokinesFemaleGene Expression RegulationGene Knockdown TechniquesGestational AgeImmune ToleranceImmunohistochemistryImmunomodulationImmunophenotypingLymph NodesLymphocyte ActivationMiceMicroRNAsBiomarkersCytokinesMicroRNAsMirn155 microRNA, mouse

Identifiers

PMID31988469
OpenAlexW3001768858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.