Evidence map›Paper›PMID 31988245›Full record

ArticleThe Journal of biological chemistry2020

Identification of the growth factor-binding sequence in the extracellular matrix protein MAGP-1.

Thomas J Broekelmann, Nicholas K Bodmer, Robert P Mecham

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Loss of MFAP5 and Its Effect on Skin Homeostasis and Wound Healing.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
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  6. Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2).Developmental dynamics : an official publication of the American Association of Anatomists · 2024
    Review
  7. MFAP2 promotes HSCs activation through FBN1/TGF-β/Smad3 pathway.Journal of cellular and molecular medicine · 2023
    Article
  8. Review
  9. Fibrillin-1 regulates endothelial sprouting during angiogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thomas J BroekelmannDepartment of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Nicholas K BodmerDepartment of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Robert P MechamDepartment of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110. Electronic address: bmecham@wustl.edu.
Washington University in St. Louis · US

Funding

PRINCIPLES IN PULMONARY RESEARCHT32HL007317 · NHLBI · WASHINGTON UNIVERSITY · PI Steven Brody, Michael J Holtzman · 1985 to 2026
$16.1M
Pediatric Cardiovascular and Pulmonary Research Training Program.T32HL125241 · NHLBI · WASHINGTON UNIVERSITY · PI Juliane Bubeck Wardenburg, Kory J. Lavine · 2015 to 2026
$4.1M
ASSEMBLY OF LUNG ELASTINR01HL053325 · NHLBI · WASHINGTON UNIVERSITY · PI MECHAM, ROBERT P. · 1995 to 2019
$3.6M
VESSEL STIFFENING, HYPERTENSION, AND VASCULAR EXTRACELLULAR MATRIXR01HL105314 · NHLBI · WASHINGTON UNIVERSITY · PI MECHAM, ROBERT P., WAGENSEIL, JESSICA · 2010 to 2018
$3.2M
NHLBI NIH HHS R01 HL053325NHLBI NIH HHS R01 HL105314NHLBI NIH HHS T32 HL007317NHLBI NIH HHS T32 HL125241
6 · The paper itself

Abstract

Microfibril-associated glycoprotein-1 (MAGP-1) is a component of vertebrate extracellular matrix (ECM) microfibrils that, together with the fibrillins, contributes to microfibril function. Many of the phenotypes associated with

Indexed as

Amino Acid SequenceAnimalsBinding SitesBone Morphogenetic ProteinsExtracellular Matrix ProteinsFibrillin-1HumansProtein BindingRNA Splicing FactorsSignal TransductionTransforming Growth Factor beta1Bone Morphogenetic ProteinsExtracellular Matrix ProteinsFibrillin-1microfibrillar proteinRNA Splicing FactorsTransforming Growth Factor beta1bone morphogenetic protein (BMP)cell signalingextracellular cellular matrix (ECM)extracellular matrixfibrillarfibrillingrowth factorgrowth factor signalingMFAP2microfibrilmicrofibril associated glycoprotein (MAGP)protein-protein interactionTGFβtransforming growth factor beta (TGFβ)

Identifiers

PMID31988245
PMCPMC7049978
OpenAlexW3004000605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.