ArticleBMJ open2020
Sex difference in incidence of gastric cancer: an international comparative study based on the Global Burden of Disease Study 2017.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
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Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.
- Immunotherapy or Targeted Therapy Versus Best Supportive Care for Advanced Gastric Cancer: A Systematic Review and Meta-analysis of Randomized Trials.Journal of gastrointestinal cancer · 2025Pooled it
- Inpatient medical costs and their composition among patients with stomach cancer who underwent surgery by tumor location: a hospital-based retrospective study in China.Cost effectiveness and resource allocation : C/E · 2026Article
- Systemic Chemotherapy in Patients with Synchronous Peritoneal Metastasis from Gastric and Esophagogastric Junction Cancers Has No Uniform Effect on the Peritoneal Cancer Index.Annals of surgical oncology · 2026Article
- Updating the Prevalence ofJournal of clinical medicine · 2026Article
- Stroke Recurrence and Long-Term Mortality in Patients Diagnosed with Cancer Following Stroke.Yonsei medical journal · 2026Observational
- Sex and Gender Differences in Patients with Gastric Cancer: A Systematic Review.Journal of clinical medicine · 2026Review
- The descriptive epidemiology of gastric cancer in Afghanistan: a population-based cancer registry, 2018-2020.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Article
- Gastrointestinal cancers in women: The role of sex hormones.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Review
- Burden of gastric cancer in individuals aged 70 and older and possible risk factors from 1990 to 2021: a population-based study.Internal and emergency medicine · 2026Article
- Sex Differences in Gastric Cancer Mortality in Ecuador: A Joinpoint Regression Analysis.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Development and Validation of Predictive Models for Gastric Neoplasm Risk Stratification in Screening Esophagogastroduodenoscopy.Gut and liver · 2025Article
- Burden and trends of early-onset gastric cancer in the 11 BRICS countries (2025 expansion): 1990-2021 with projections to 2035.BMC cancer · 2025Article
- Impact of adjuvant therapy on outcomes of cancer of the stomach and gastroesophageal junction in the real-world.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025Article
- Epidemiology and socioeconomic factors of nonmelanoma skin cancer in the Middle East and North Africa 1990 to 2021.Scientific reports · 2025Article
- Article
- Delay Patterns and Associated Factors Among Gastric Cancer Patients Visiting Tertiary Hospital in Ethiopia.Cancer reports (Hoboken, N.J.) · 2025Article
- Epidemiology and socioeconomic correlates of gastric cancer in Asia: results from the GLOBOCAN 2020 data and projections from 2020 to 2040.Scientific reports · 2025Article
- Stomach cancer epidemic in Chinese mainland: Current trends and future predictions.Chinese medical journal · 2025Article
- Trends in gastric cancer burden in the Western Pacific region from 1990 to 2021 and projections to 2040.Frontiers in oncology · 2025Article
- A surveillance study of cancer incidence and mortality among young adults in Costa Rica.Lancet regional health. Americas · 2024Article
4 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate sex difference in global gastric cancer incidence by year, age and socioeconomical status.
designAn international comparative study.
settingWe obtained the global and national sex-specific incidence of gastric caner by year and age from the Global Burden of Disease Study 2017. The human development index (HDI) in 2017 as an indicator of national socioeconomical status was extracted from the Human Development Report.
main outcome measuresSex-specific incidence of gastric cancer was compared by year and age at the global level. Linear regression analyses were performed to explore socioeconomic-associated sex difference in gastric cancer incidence.
resultsDespite declining incidence of global gastric cancer in both sexes between 1990 and 2017, relative sex difference showed an increasing trend, with male to female ratios of age-standardised incidence rates (ASRs) rising from 1.86 to 2.20. Sex difference was almost negligible under 45 years of age and relative difference maximised in the age range of 65-69 years with male to female ratios of ASRs being 2.74. Both absolute sex difference (standardised β=0.256, p<0.001) and relative difference (standardised β=0.387, p<0.001) in ASRs were positively associated with HDI.
conclusionsThis study revealed that decreasing incidence of global gastric cancer was accompanied by widening sex difference in the past few decades. Men always had higher incidence than women. Greater sex difference was found in older age and in more developed countries. These findings highlight the importance of making sex-sensitive health policy to cope with the global gastric cancer burden.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.