Evidence map›Paper›PMID 31988203›Full record

ReviewCold Spring Harbor perspectives in medicine2021

Swine Influenza A Viruses and the Tangled Relationship with Humans.

Tavis K Anderson, Jennifer Chang, Zebulun W Arendsee, Divya Venkatesh, Carine K Souza, J Brian Kimble, Nicola S Lewis, C Todd Davis, Amy L Vincent

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed.

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  17. Passive surveillance for Influenza A virus among swine, Brazil, 2009-2023.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
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77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tavis K AndersonVirus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa 50010, USA.
Jennifer ChangVirus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa 50010, USA.
Zebulun W ArendseeVirus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa 50010, USA.
Divya VenkateshDepartment of Pathology and Population Sciences, Royal Veterinary College, University of London, Hertfordshire AL9 7TA, United Kingdom.
Carine K SouzaVirus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa 50010, USA.
J Brian KimbleVirus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa 50010, USA.
Nicola S LewisDepartment of Pathology and Population Sciences, Royal Veterinary College, University of London, Hertfordshire AL9 7TA, United Kingdom.
C Todd DavisInfluenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Amy L VincentVirus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa 50010, USA.

Funding

NIAID NIH HHS HHSN272201400008C
6 · The paper itself

Abstract

Influenza A viruses (IAVs) are the causative agents of one of the most important viral respiratory diseases in pigs and humans. Human and swine IAV are prone to interspecies transmission, leading to regular incursions from human to pig and vice versa. This bidirectional transmission of IAV has heavily influenced the evolutionary history of IAV in both species. Transmission of distinct human seasonal lineages to pigs, followed by sustained within-host transmission and rapid adaptation and evolution, represent a considerable challenge for pig health and production. Consequently, although only subtypes of H1N1, H1N2, and H3N2 are endemic in swine around the world, extensive diversity can be found in the hemagglutinin (HA) and neuraminidase (NA) genes, as well as the remaining six genes. We review the complicated global epidemiology of IAV in swine and the inextricably entangled implications for public health and influenza pandemic planning.

Indexed as

AnimalsHemagglutination Inhibition TestsHumansInfluenza A virusInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H1N2 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza, HumanOrthomyxoviridae InfectionsPhylogenySwine

Identifiers

PMID31988203
PMCPMC7919397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.