Evidence map›Paper›PMID 31988187›Full record

ArticleDevelopment (Cambridge, England)2020

Different modes of Notch activation and strength regulation in the spermathecal secretory lineage.

Wei Shen, Jianjun Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Finishing the egg.Genetics · 2024
    Article
  2. Review
  3. Biological Significance of NOTCH Signaling Strength.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wei ShenDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269, USA.ORCID 0000-0002-2420-8311
Jianjun SunDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269, USA jianjun.sun@uconn.edu.ORCID 0000-0002-6015-738X

Funding

Genetic interrogation of conserved follicular factors for matrix metalloproteinase regulation and ovulationR01HD086175 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI SUN, JIANJUN · 2016 to 2020
$1.7M
NICHD NIH HHS R01 HD086175
6 · The paper itself

Abstract

The strength of Notch signaling contributes to pleiotropic actions of Notch; however, we do not yet have a full understanding of the molecular regulation of Notch-signaling strength. We have investigated the mode of Notch activation in binary fate specification in the

Indexed as

AnimalsAnimals, Genetically ModifiedCell DifferentiationCell LineageDrosophilaDrosophila ProteinsEndosomesFemaleGene Knockdown TechniquesGenitaliaIntracellular Signaling Peptides and ProteinsJagged-1 ProteinLigandsMaleMembrane ProteinsReceptors, Notchdelta proteinDrosophila ProteinsIntracellular Signaling Peptides and ProteinsJagged-1 ProteinLigandsMembrane ProteinsN protein, DrosophilaReceptors, NotchRepressor ProteinsSer protein, DrosophilaSu(H) protein, DrosophilaAsymmetric Notch activationDeltexNotch signaling strengthNumbRab5

Identifiers

PMID31988187
PMCPMC7033723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.