Evidence map›Paper›PMID 31988174›Full record

ArticleInfection and immunity2020

Transposon Mutagenesis Screen of Klebsiella pneumoniae Identifies Multiple Genes Important for Resisting Antimicrobial Activities of Neutrophils in Mice.

Michelle K Paczosa, Rebecca J Silver, Anne L McCabe, Albert K Tai, Colin H McLeish, David W Lazinski, Joan Mecsas

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Effective macrophage clearance ofbioRxiv : the preprint server for biology · 2026
    Article
  3. Infection and immunity · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Revealing fitness and virulence determinants of hypervirulentFrontiers in cellular and infection microbiology · 2025
    Article
  8. Deciphering the gastrointestinal carriage ofInfection and immunity · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Michelle K Paczosa *Graduate Program in Immunology, MERGE-ID Track, Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, USA.
Rebecca J Silver *Graduate Program in Immunology, MERGE-ID Track, Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, USA.
Anne L McCabeDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Albert K TaiDepartment of Immunology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Colin H McLeishDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
David W LazinskiDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Joan MecsasDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA Joan.mecsas@tufts.edu.ORCID 0000-0001-9455-6672
Tufts University · US

Funding

Tufts IRACDAK12GM133314 · NIGMS · TUFTS UNIVERSITY BOSTON · PI CLAIRE L MOORE, Jamie Lynn Maguire · 2019 to 2026
$8.4M
MOLECULAR ANALYSIS OF MICROBIAL PATHOGENST32AI007422 · NIAID · TUFTS UNIVERSITY BOSTON · PI Ralph R. Isberg · 1992 to 2026
$5.7M
IMMUNOLOGIC ASPECTS OF DISEASET32AI007077 · NIAID · TUFTS UNIVERSITY BOSTON · PI WORTIS, HENRY H. · 1985 to 2017
$3.5M
Initiation and regulation of antibacterial innate immunityR01AI113166 · NIAID · TUFTS UNIVERSITY BOSTON · PI MECSAS, JOAN C · 2014 to 2018
$2.4M
Bifunctional Control of Yop Translocation by YopKR01AI107055 · NIAID · TUFTS UNIVERSITY BOSTON · PI MARKETON, MELANIE · 2013 to 2017
$1.9M
NIAID NIH HHS R01 AI107055NIAID NIH HHS R01 AI113166NIAID NIH HHS T32 AI007077NIAID NIH HHS T32 AI007422NIGMS NIH HHS K12 GM133314
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Host-Pathogen InteractionsAnimalsDisease Models, AnimalDNA Transposable ElementsGenetic TestingKlebsiella InfectionsKlebsiella pneumoniaeMiceMutagenesis, InsertionalNeutrophilsPneumonia, BacterialVirulenceVirulence FactorsDNA Transposable ElementsVirulence FactorsdedAgntRKlebsiellaKlebsiella pneumoniaelung infectionneutropeniaTn-seqwzmyaaAycgE

Identifiers

PMID31988174
PMCPMC7093148
OpenAlexW3003676607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.