Evidence map›Paper›PMID 31988104›Full record

ArticleAntimicrobial agents and chemotherapy2020

Antiviral Activity of Tenofovir Alafenamide against HIV-1 with Thymidine Analog-Associated Mutations and M184V.

Nicolas Margot, Renee Ram, Michael Abram, Richard Haubrich, Christian Callebaut

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicolas Margot *Gilead Sciences, Inc., Foster City, California, USA nicolas.margot@gilead.com.ORCID 0000-0002-0911-4237
Renee Ram *Gilead Sciences, Inc., Foster City, California, USA.
Michael AbramGilead Sciences, Inc., Foster City, California, USA.
Richard HaubrichGilead Sciences, Inc., Foster City, California, USA.
Christian CallebautGilead Sciences, Inc., Foster City, California, USA.
Gilead Sciences (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tenofovir alafenamide (TAF) and tenofovir disoproxil fumarate (TDF) are prodrugs of the HIV-1 nucleotide reverse transcriptase inhibitor tenofovir (TFV).

Indexed as

MutationAdenineAlanineAnti-HIV AgentsDrug Resistance, ViralHIV-1HIV InfectionsHumansMicrobial Sensitivity TestsMutagenesis, Site-DirectedProdrugsTenofovirThymidineAdenineAlanineAnti-HIV AgentsProdrugsTenofovirtenofovir alafenamideThymidineantiretroviral resistanceHIV-1M184VTAFTAMstenofovir alafenamidethymidine analog-associated mutations

Identifiers

PMID31988104
PMCPMC7179327
OpenAlexW3002403602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.