Evidence map›Paper›PMID 31988092›Full record

ArticleBiology open2020

Ravindra Singh Prajapati, Richard Mitter, Annalisa Vezzaro, David Ish-Horowicz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. The vertebrate Embryo Clock: Common players dancing to a different beat.Frontiers in cell and developmental biology · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ravindra Singh PrajapatiCancer Research UK Developmental Genetics Laboratory, CRUK London Research Institute.ORCID 0000-0002-6173-6615
Richard MitterCancer Research UK Developmental Genetics Laboratory, CRUK London Research Institute.ORCID 0000-0002-1279-3760
Annalisa VezzaroCancer Research UK Developmental Genetics Laboratory, CRUK London Research Institute.
David Ish-HorowiczCancer Research UK Developmental Genetics Laboratory, CRUK London Research Institute d.ish-horowicz@ucl.ac.uk.ORCID 0000-0001-5684-7129
Cancer Research UK · GBThe Francis Crick Institute · GB

Funding

Cancer Research UK
6 · The paper itself

Abstract

During vertebrate embryonic development, the formation of axial structures is driven by a population of stem-like cells that reside in a region of the tailbud called the chordoneural hinge (CNH). We have compared the mouse CNH transcriptome with those of surrounding tissues and shown that the CNH and tailbud mesoderm are transcriptionally similar, and distinct from the presomitic mesoderm. Amongst CNH-enriched genes are several that are required for axial elongation, including

Indexed as

AnimalsComputational BiologyEmbryonic DevelopmentGene Expression ProfilingGene Expression Regulation, DevelopmentalGene Knockdown TechniquesMembrane ProteinsMiceMorphogenesisNeoplasm ProteinsPhenotypeStem CellsTranscriptomeZebrafish Proteinsgreb1 protein, zebrafishKIAA0575 protein, mouseMembrane ProteinsNeoplasm ProteinsZebrafish ProteinsAxial stem cellsClockNeural tubeProgenitorsSomitesTailbudTranscriptome

Identifiers

PMID31988092
PMCPMC7044451
OpenAlexW3003895138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.