SynthesisThe British journal of general practice : the journal of the Royal College of General Practitioners2020
Increased fluid intake to prevent urinary tract infections: systematic review and meta-analysis.
Synthesis in The British journal of general practice : the journal of the Royal College of General Practitioners, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Natural history of uncomplicated urinary tract infection without antibiotics: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020Pooled it
- Women's Experiences of Recurrent UTIs: A Qualitative Study of Preventive Management and Decision Support Needs.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- A nomogram estimates postoperative urinary tract infection risk after upper urinary tract stone surgery with double-J stents.Scientific reports · 2026Observational
- Trends and burden of urolithiasis in China, 1990-2021: a systematic analysis of the global burden of disease study 2021 with future projections to 2036.World journal of urology · 2025Article
- Different factors control long-term versus short-term outcomes for bacterial colonisation of a urinary catheter.Nature communications · 2025Article
- Clinical Recommendations for Managing Genitourinary Adverse Effects in Patients Treated with SGLT-2 Inhibitors: A Multidisciplinary Expert Consensus.Journal of clinical medicine · 2024Review
- A Perspective on the Interaction Between Recurrent Lower Urinary Tract Infections and Irritable Bowel Syndrome.Nutrients · 2024Article
- Recurrent Urinary Tract Infection in Older Outpatient Women.JAMA internal medicine · 2024Article
- The Diagnosis, Treatment, and Prevention of Recurrent Urinary Tract Infection.Deutsches Arzteblatt international · 2024Review
- Conceptual framework for preterm birth review in San Francisco.Frontiers in public health · 2024Article
- Management of urinary tract infections in the community: a clinical audit and patient survey.BJGP open · 2023Article
- Community-Acquired Urinary Tract Infection Among Sexually Active Women: Risk Factors, Bacterial Profile and Their Antimicrobial Susceptibility Patterns, Arba Minch, Southern Ethiopia.Infection and drug resistance · 2023Article
- The Clinical Trial Outcomes of Cranberry, D-Mannose and NSAIDs in the Prevention or Management of Uncomplicated Urinary Tract Infections in Women: A Systematic Review.Pathogens (Basel, Switzerland) · 2022Review
- Guideline of guidelines: management of recurrent urinary tract infections in women.BJU international · 2022Review
- [Correlation between daily fluid intake behavioral habits and pathological characteristics of upper tract urothelial carcinoma].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022Article
- Innate Bacteriostatic Mechanisms Defend the Urinary Tract.Annual review of physiology · 2022Review
- Article
- Occurrence of urinary tract infection and preventive strategies practiced by female students at a tertiary care teaching institution.Journal of education and health promotion · 2022Article
- Womens' self-management skills for prevention and treatment of recurring urinary tract infection.International journal of clinical practice · 2021Article
- Unraveling the vaginal microbiota-based etiology of recurrent cystitis: the potential role ofTherapeutic advances in urologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundApproximately 15% of community-prescribed antibiotics are used in treating urinary tract infections (UTIs). Increase in antibiotic resistance necessitates considering alternatives.
aimTo assess the impact of increased fluid intake in individuals at risk for UTIs, for impact on UTI recurrence (primary outcome), antimicrobial use, and UTI symptoms (secondary outcomes). DESIGN AND
settingA systematic review.
methodThe authors searched PubMed, Cochrane CENTRAL, EMBASE, two trial registries, and conducted forward and backward citation searches of included studies in January 2019. Randomised controlled trials of individuals at risk for UTIs were included; comparisons with antimicrobials were excluded. Different time-points (≤6 months and 12 months) were compared for the primary outcome. Risk of bias was assessed using Cochrane Risk of Bias tool. Meta-analyses were undertaken where ≥3 studies reported the same outcome.
resultsEight studies were included; seven were meta-analysed. There was a statistically non-significant reduction in the number of patients with any UTI recurrence in the increased fluid intake group compared with control after 12 months (odds ratio [OR] 0.39, 95% confidence interval [CI] = 0.15 to 1.03,
conclusionGiven the minimal potential for harm, patients with recurrent UTIs could be advised to drink more fluids to reduce recurrent UTIs. Further research is warranted to establish the optimal volume and type of increased fluid.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.