Evidence map›Paper›PMID 31988051›Full record

ArticleBMJ case reports2020

Primary spinal epidural lymphoma: a rare entity with an ambiguous management.

João Páscoa Pinheiro, Joana Rato, Olinda Rebelo, Gonçalo Costa

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

João Páscoa PinheiroDepartment of Neurosurgery, Coimbra University Hospital Centre, Coimbra, Portugal jpascoapinheiro@gmail.com.ORCID http://orcid.org/0000-0001-6298-7435
Joana RatoDepartment of Neurosurgery, Coimbra University Hospital Centre, Coimbra, Portugal.
Olinda RebeloDepartment of Neurology, Coimbra University Hospital Centre, Coimbra, Portugal.
Gonçalo CostaDepartment of Neurosurgery, Coimbra University Hospital Centre, Coimbra, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphomas are malignant lymphoid tumours arising from lymphocytic cells. They usually develop in the lymphoid tissues and can spread to other organs; however, primary extra-nodal locations such as the spinal epidural space are less common. The authors report the case of a primary diffuse large B-cell lymphoma of the thoracic spine in a 65-year-old man, who presented to the emergency department with signs of upper motor neuron lesion. The patient underwent surgery in order to decompress the spinal cord. The treatment was concluded with six cycles of chemotherapy with methotrexate, rituximab, cyclophosphamide, vincristine and prednisone followed by radiotherapy. At the 24-month follow-up, no signs of epidural lesion or bone contrast enhancement were observed in thoracic spine MRI. Surgical decompression is recommended in patients with signs of spinal cord injury in order to prevent irreversible neurological damage and is related to high rates of disease-free survival.

Indexed as

AgedCyclophosphamideDecompression, SurgicalEpidural SpaceHumansLaminectomyLymphoma, Large B-Cell, DiffuseMagnetic Resonance ImagingMaleMethotrexatePrednisoneRituximabVincristineCyclophosphamideMethotrexatePrednisoneRituximabVincristineneurosurgerysurgical oncology

Identifiers

PMID31988051
PMCPMC7035830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.