Evidence map›Paper›PMID 31987814›Full record

ReviewFrontiers in neuroendocrinology2020

Pregnancy, postpartum and parity: Resilience and vulnerability in brain health and disease.

Nicholas P Deems, Benedetta Leuner

Open access · greenAbstract readReview
In one paragraph

Review in Frontiers in neuroendocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. [Clinical and obstetric characteristics in women with multiple sclerosis during pregnancy].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Beyond Birth Control: The Neuroscience of Hormonal Contraceptives.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  12. Article
  13. Article
  14. Connections between reproductive health and cognitive aging among women enrolled in the HCHS/SOL and SOL-INCA.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicholas P DeemsThe Ohio State University, Department of Psychology, Columbus, OH, USA.
Benedetta LeunerThe Ohio State University, Department of Psychology, Columbus, OH, USA. Electronic address: leuner.1@osu.edu.
The Ohio State University · US

Funding

Gestational stress effects on neuroimmune function during the peripartum periodR21MH117482 · NIMH · OHIO STATE UNIVERSITY · PI LENZ, KATHRYN M., LEUNER, BENEDETTA J · 2019 to 2020
$416k
NIMH NIH HHS R21 MH117482
6 · The paper itself

Abstract

Risk and resilience in brain health and disease can be influenced by a variety of factors. While there is a growing appreciation to consider sex as one of these factors, far less attention has been paid to sex-specific variables that may differentially impact females such as pregnancy and reproductive history. In this review, we focus on nervous system disorders which show a female bias and for which there is data from basic research and clinical studies pointing to modification in disease risk and progression during pregnancy, postpartum and/or as a result of parity: multiple sclerosis (MS), depression, stroke, and Alzheimer's disease (AD). In doing so, we join others (Shors, 2016; Galea et al., 2018a) in aiming to illustrate the importance of looking beyond sex in neuroscience research.

Indexed as

Central Nervous SystemNervous System DiseasesAlzheimer DiseaseAnimalsDepression, PostpartumFemaleHumansMultiple SclerosisParityPostpartum PeriodPregnancyPregnancy ComplicationsRisk FactorsSex CharacteristicsSex FactorsStrokeAllogregnanoloneAlzheimer’s diseaseEstrogenFetal microchimerismImmuneMaternalMultiple sclerosisPostpartum depressionProgesteroneProlactinStroke

Identifiers

PMID31987814
PMCPMC7225072
OpenAlexW3002548789

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.