Evidence map›Paper›PMID 31987069›Full record

ArticleeLife2020

Zika seroprevalence declines and neutralizing antibodies wane in adults following outbreaks in French Polynesia and Fiji.

Alasdair D Henderson, Maite Aubry, Mike Kama, Jessica Vanhomwegen, Anita Teissier, Teheipuaura Mariteragi-Helle, Tuterarii Paoaafaite, Yoann Teissier, Jean-Claude Manuguerra, John Edmunds and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Evidence of Ongoing Transmission of Zika Virus in Mérida, Mexico.The American journal of tropical medicine and hygiene · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 5 countries.

Alasdair D Henderson *Centre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Maite Aubry *Institut Louis Malardé, Papeete, French Polynesia.
Mike KamaFiji Centre for Communicable Disease Control, Suva, Fiji.
Jessica VanhomwegenInstitut Pasteur, Paris, France.
Anita TeissierInstitut Louis Malardé, Papeete, French Polynesia.
Teheipuaura Mariteragi-HelleInstitut Louis Malardé, Papeete, French Polynesia.
Tuterarii PaoaafaiteInstitut Louis Malardé, Papeete, French Polynesia.
Yoann TeissierDirection de la Santé de la Polynésie française, Papeete, French Polynesia.
Jean-Claude ManuguerraInstitut Pasteur, Paris, France.ORCID http://orcid.org/0000-0002-5202-6531
John EdmundsCentre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Jimmy WhitworthCentre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Conall H WatsonCentre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Colleen L LauAustralian National University, Canberra, Australia.
Van-Mai Cao-Lormeau *Institut Louis Malardé, Papeete, French Polynesia.
Adam J Kucharski *Centre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID https://orcid.org/0000-0001-8814-9421
Institut Louis Malardé · PFLondon School of Hygiene & Tropical Medicine · GBInstitut Pasteur · FRAustralian National University · AUUniversity of French Polynesia · PFUniversity of the South Pacific · FJ

Funding

French and French Polynesia government MA'I'ORE program 03298/MTF/REC-17/05/18French and French Polynesia government MA'I'ORE program HC/245/DIE/BPT-16/05/19French and French Polynesia government MA'I'ORE program HC/372/DIE/BPT- 18/05/18Horizon 2020 - Research and Innovation Framework Programme ZIKAlliance grant 734548Investissement d'Avenir Program Labex IBEID grant ANR-10-LABX-62- IBEIDMedical Research Council MR/J003999/1Medical Research Council MR/N013638/1Ministry for Europe and Foreign Affairs Pacific funds 04917-19/07/17Ministry of Europe and Foreign Affairs Pacific funds 02918-18/06/18National Health and Medical Research Council 1109035Wellcome 107778/Z/15/ZWellcome 206250/Z/17/ZWellcome Trust
6 · The paper itself

Abstract

It has been commonly assumed that Zika virus (ZIKV) infection confers long-term protection against reinfection, preventing ZIKV from re-emerging in previously affected areas for several years. However, the long-term immune response to ZIKV following an outbreak remains poorly documented. We compared results from eight serological surveys before and after known ZIKV outbreaks in French Polynesia and Fiji, including cross-sectional and longitudinal studies. We found evidence of a decline in seroprevalence in both countries over a two-year period following first reported ZIKV transmission. This decline was concentrated in adults, while high seroprevalence persisted in children. In the Fiji cohort, there was also a significant decline in neutralizing antibody titres against ZIKV, but not against dengue viruses that circulated during the same period.

Indexed as

Antibodies, NeutralizingAdolescentAdultAgedAged, 80 and overAntibodies, ViralBlood DonorsChildChild, PreschoolCross-Sectional StudiesDisease OutbreaksFijiHealth SurveysHumansImmunoglobulin GInfantAntibodies, NeutralizingAntibodies, ViralImmunoglobulin Gantibody responsedengueepidemiologyglobal healthhumaninfectious diseasemicrobiologyseroprevalenceZika

Identifiers

PMID31987069
PMCPMC6986872
OpenAlexW3003228911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.