Evidence map›Paper›PMID 31986239›Full record

ArticlePediatric obesity2020

Evaluating body composition in infancy and childhood: A comparison between 4C, QMR, DXA, and ADP.

Melissa E Heard-Lipsmeyer, Holly Hull, Clark R Sims, Mario A Cleves, Aline Andres

Open access · greenAbstract readComparative Study
In one paragraph

Article in Pediatric obesity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Melissa E Heard-LipsmeyerArkansas Children's Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, Arkansas.ORCID 0000-0003-4655-2452
Holly HullDepartment of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, Kansas.
Clark R SimsArkansas Children's Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Mario A ClevesArkansas Children's Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Aline AndresArkansas Children's Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, Arkansas.ORCID 0000-0003-2611-2193
Arkansas Children's Hospital · USUniversity of Kansas Medical Center · US

Funding

Maternal and Infant Added Sugars Intake in Relation to Infant Adipose Tissue AccrualR01DK118220 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI HULL, HOLLY RENEE · 2018 to 2022
$3.1M
Phenotypic and metabolic characteristics in early childhood leading to obesityR01DK107516 · NIDDK · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI ANDRES, ALINE, BORSHEIM, ELISABET · 2016 to 2020
$1.6M
NIDDK NIH HHS R01 DK107516NIDDK NIH HHS R01 DK118220
6 · The paper itself

Abstract

backgroundAccurate and precise methods to measure of body composition in infancy and childhood are needed.

objectivesThis study evaluated differences and precision of three methods when compared with the four-compartment (4C) model for estimating fat mass (FM).

methodsFM of children (age 14 days to 6 years of age, N = 346) was obtained using quantitative nuclear magnetic resonance (QMR, EchoMRI-AH), air-displacement plethysmography (ADP, PeaPod, less than or equal to 8 kg, BodPod age 6 years or older), and dual-energy X-ray absorptiometry (DXA, Hologic QDR). The 4C model was computed. Correlation, concordance, and Bland-Altman analyses were performed.

resultsIn infants, PeaPod had high individual FM accuracy, whereas DXA had high group FM accuracy compared with 4C. In children, DXA had high group and individual FM accuracies compared with 4C. QMR underestimated group FM in infants and children (300 and 510 g, respectively). The instrument FM precision was best for QMR (10 g) followed by BodPod (34 g), PeaPod (38 g), and DXA (45 g).

conclusionsIn infants, PeaPod was the best method to estimate individual FM whereas DXA was best to estimate group FM. In children, DXA was best to estimate individual and group FM. QMR had the highest instrument precision.

Indexed as

Body CompositionAbsorptiometry, PhotonAdipose TissueChildChild, PreschoolFemaleHumansInfantInfant, NewbornMagnetic Resonance SpectroscopyMalePlethysmographyair displacement plethysmographybody compositiondual-energy X-ray absorptiometryfat massquantitative nuclear magnetic resonance

Identifiers

PMID31986239
PMCPMC7323309
OpenAlexW3004133088

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.