Evidence map›Paper›PMID 31986064›Full record

SynthesisJournal of clinical oncology : official journal of the American Society of Clinical Oncology2020

Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer: ASCO Guideline.

Panagiotis A Konstantinopoulos, Barbara Norquist, Christina Lacchetti, Deborah Armstrong, Rachel N Grisham, Paul J Goodfellow, Elise C Kohn, Douglas A Levine, Joyce F Liu, Karen H Lu and 2 more

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
186citing papers in PubMed, 12 pooled it
41.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

186 citing papers in PubMed, 12 syntheses or guidelines pooled it, 362 citations in OpenAlex.

  1. Morphological and molecular characterization of epithelial ovarian cancer: SEOM-SEAP consensus guidelines for biomarker integration in clinical practice.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Guideline
  2. Pooled it
  3. Neoadjuvant Chemotherapy for Newly Diagnosed, Advanced Ovarian Cancer: ASCO Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Guideline
  4. SEOM-GEICO clinical guideline on epithelial ovarian cancer (2023).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Guideline
  5. Guideline
  6. Guideline
  7. Systematic mapping review of guidelines forInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023
    Pooled it
  8. Pooled it
  9. Pooled it
  10. Guideline
  11. Pooled it
  12. PARP Inhibitors in the Management of Ovarian Cancer: ASCO Guideline.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020
    Guideline
  13. Testing a Population-Based Outreach Intervention for Ovarian Cancer Survivors to Encourage their Close Relatives to Consider Genetic Counseling.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Trial
  14. Article
  15. Review
  16. Review
  17. SEOM‑GETTHI clinical guideline for the practical management of molecular platforms (update 2026).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  18. Article
  19. Article
  20. Article

126 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Commented on by
    2020
5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Panagiotis A KonstantinopoulosDana-Farber Cancer Institute, Boston, MA.
Barbara NorquistUniversity of Washington Medicine, Seattle, WA.
Christina LacchettiAmerican Society of Clinical Oncology, Alexandria, VA.
Deborah ArmstrongJohns Hopkins, Baltimore, MD.
Rachel N GrishamMemorial Sloan Kettering Cancer Center, New York, NY.
Paul J GoodfellowOhio State University Comprehensive Cancer Center, Columbus, OH.
Elise C KohnGynecologic Cancer Therapeutics, National Cancer Institute, Bethesda, MD.
Douglas A LevineNYU Langone Health, New York, NY.
Joyce F LiuDana-Farber Cancer Institute, Boston, MA.
Karen H LuThe University of Texas MD Anderson Cancer Center, Houston,TX.
Dorinda SparacioPatient Representative, Hightstown, NJ.
Christina M AnnunziataWomen's Malignancies Branch, National Cancer Institute, Bethesda, MD.
Dana-Farber Cancer Institute · USNational Cancer Institute · USAmerican Society of Clinical Oncology · USJohns Hopkins University · USMemorial Sloan Kettering Cancer Center · USNYU Langone Health · USThe Ohio State University · USThe University of Texas MD Anderson Cancer Center · USUniversity of Washington · US

Funding

Clinical trials in womens cancersZIABC011584 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ANNUNZIATA, CHRISTINA · 2014 to 2023
$3.1M
Intramural NIH HHS ZIA BC011584
6 · The paper itself

Abstract

purposeTo provide recommendations on genetic and tumor testing for women diagnosed with epithelial ovarian cancer based on available evidence and expert consensus.

methodsA literature search and prospectively defined study selection criteria sought systematic reviews, meta-analyses, randomized controlled trials (RCTs), and comparative observational studies published from 2007 through 2019. Guideline recommendations were based on the review of the evidence.

resultsThe systematic review identified 19 eligible studies. The evidence consisted of systematic reviews of observational data, consensus guidelines, and RCTs. RECOMMENDATIONS: All women diagnosed with epithelial ovarian cancer should have germline genetic testing for

Indexed as

Genes, BRCA1Genes, BRCA2Genetic TestingGerm-Line MutationCarcinoma, Ovarian EpithelialFemaleGenetic CounselingHealth Status DisparitiesHumansOvarian NeoplasmsPractice Guidelines as TopicRandomized Controlled Trials as Topic

Identifiers

PMID31986064
PMCPMC8842911
OpenAlexW3001210504

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.