Evidence map›Paper›PMID 31985386›Full record

ReviewEndocrine, metabolic & immune disorders drug targets2020

Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Acromegaly - Part 1: Diagnostic and Clinical Issues.

Renato Cozzi, Maria R Ambrosio, Roberto Attanasio, Alessandro Bozzao, Laura De Marinis, Ernesto De Menis, Edoardo Guastamacchia, Andrea Lania, Giovanni Lasio, Francesco Logoluso and 6 more

Abstract readReviewConsensus Statement
In one paragraph

Review in Endocrine, metabolic & immune disorders drug targets, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Renato CozziDivision of Endocrinology, Niguarda Hospital, Milan, Italy.
Maria R AmbrosioSection of Endocrinology and Internal Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Roberto AttanasioIRCCS Orthopedic Institute Galeazzi, Endocrinology Service, Mila, Italy.
Alessandro BozzaoNeuroradiology, S. Andrea Hospital, NESMOS Department (Neuroscience, Mental Health, Sensorial Organs), Sapienza University of Rome, Rome, Italy.
Laura De MarinisPituitary Unit, Department of Endocrinology, Catholic University of the Sacred Heart, School of Medicine, Rome, Italy.
Ernesto De MenisDepartment of Internal Medicine, General Hospital, Montebelluna (TV), Italy.
Edoardo GuastamacchiaAME President, University of Bari, Bari, Italy.
Andrea LaniaDepartment of Biomedical Sciences, IRCCS Humanitas University and Endocrinology Unit, Humanitas Research Hospital, Rozzano, Italy.
Giovanni LasioDepartment of Neurosurgery, Humanitas University and Endocrinology Unit, Humanitas Research Hospital, Rozzano, Italy.
Francesco LogolusoEndocrinology Unit, Department of Emergency and Organ Transplantation, University Medical School 'Aldo Moro', Bari, Italy.
Pietro MaffeiDepartment of Medicine (DIMED), 3rd Medical Clinic, Padua University Hospital, Padua, Italy.
Maurizio PoggiEndocrinology, Department of Clinical and Molecular Medicine, S. Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Vincenzo ToscanoEndocrinology, Department of Clinical and Molecular Medicine, S. Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Michele ZiniEndocrinology Unit, Azienda Ospedaliera S. Maria Nuova IRCCS, Reggio Emilia, Italy.
Philippe ChansonEndocrinology and Reproductive Diseases, Bicêtre Hospital and Paris-Saclay University 11, France.
Laurence KatznelsonDepartment of Medicine, Stanford University Hospital, Stanford, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acromegaly is a rare disease. Improvements in lifespan in these patients have recently been reported due to transsphenoidal surgery (TSS), advances in medical therapy, and strict criteria for defining disease remission. This document reports the opinions of a group of Italian experts who have gathered together their prolonged clinical experience in the diagnostic and therapeutic challenges of acromegaly patients. Both GH and IGF-I (only IGF-I in those treated with Pegvisomant) are needed in the diagnosis and follow-up. Comorbidities (cardio-cerebrovascular disease, sleep apnea, metabolic derangement, neoplasms, and bone/joint disease) should be specifically addressed. Any newly diagnosed patient should be referred to a multidisciplinary team experienced in the treatment of pituitary adenomas.

Indexed as

AcromegalyEndocrinologistsHuman Growth HormoneHumansInsulin-Like Growth Factor IItalyPractice Guidelines as TopicSocieties, MedicalHuman Growth HormoneIGF1 protein, humanInsulin-Like Growth Factor IAcromegalycomorbiditiesdiscrepantGHIGF-Ipituitary

Identifiers

PMID31985386
PMCPMC7579251

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.