Evidence map›Paper›PMID 31985125›Full record

Trial reportThe oncologist2020

A Randomized Trial of Real-Time Geriatric Assessment Reporting in Nonelectively Hospitalized Older Adults with Cancer.

Trevor A Jolly, Allison M Deal, Caroline Mariano, Nicole Markowski, Sharanda Kirk, Max S Perlmutt, Franklin Jones, Suel Ki Choi, Kirsten A Nyrop, Jan Busby-Whitehead and 1 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The oncologist, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Informational support for depression and quality of life improvements in older patients with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Trevor A JollyDivision of Hematology and Oncology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0003-2900-848X
Allison M DealLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Caroline MarianoRoyal Columbian Hospital Medical Oncology, New Westminster, British Columbia, Canada.
Nicole MarkowskiLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Sharanda KirkLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Max S PerlmuttLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Franklin JonesLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Suel Ki ChoiGillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
Kirsten A NyropDivision of Hematology and Oncology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Jan Busby-WhiteheadCenter for Aging and Health/Division of Geriatric Medicine, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Hyman MussDivision of Hematology and Oncology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
University of North Carolina at Chapel Hill · USUNC Lineberger Comprehensive Cancer CenterRoyal Columbian Hospital · CA

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
NCI NIH HHS P30 CA016086
6 · The paper itself

Abstract

backgroundHospitalized older adults have significant geriatric deficits that may lead to poor outcomes. We conducted a randomized trial to investigate the effectiveness of providing clinicians with a real-time geriatric assessment (GA) report in nonelectively hospitalized older patients with cancer. SUBJECTS, MATERIALS, AND

methodsWe developed a web-based software platform for administering a modified GA (Cancer 2005;104:1998-2005) to older (>70 years) nonelectively hospitalized patients with pathologically confirmed malignancy. Patients were randomized to have their GA report provided to their treating clinicians (Intervention arm) or not provided (Control arm).

resultsOur study included 135 patients, median age 76 years, 52% female, 75% white, 21% black, 79% greater than high school education, 59% married, and 17% living alone. All patients had at least one GA-identified deficit, including physical function deficits (90%), cognitive impairment (22%), >5 comorbidities (28%), polypharmacy (>9 medications; 38%), weight loss ≥10% in the past 6 months (40%), anxiety (32%), or depression (30%). There was no difference between the Intervention (6%) and Control arms (9%) in the proportion of patients who were referred by their clinical team for an intervention to address a deficit (p = .53).

conclusionMany older nonelectively hospitalized patients with cancer have geriatric deficits that are amenable to evidence-based interventions. Real-time GA reports provided to the care team prior to discharge did not influence provider referral for such interventions. There is a need for systems-level interventions to address deficits in this vulnerable patient population. IMPLICATIONS FOR PRACTICE: Geriatric deficits are common in hospitalized older adults with cancer and lead to poor outcomes. Addressing modifiable deficits represents an appealing way to improve outcomes. Widespread geriatrician consultation is impractical owing to resource and personnel constraints. This work tested whether prompt delivery of a mostly self-administered, web-based geriatric assessment report to clinicians improved referral rates for evidence-informed interventions. It confirmed frequent geriatric deficits and high readmission rates in this population but found that real-time geriatric assessment reporting did not influence provider referral for evidence-informed interventions on geriatric assessment identified deficits. These findings highlight the need for systems-level intervention to improve outcomes in this vulnerable patient population.

Indexed as

Geriatric AssessmentNeoplasmsAgedComorbidityFemaleHumansMalePolypharmacyReferral and ConsultationCancer and agingGeriatric assessmentGeriatric oncology

Identifiers

PMID31985125
PMCPMC7288650
OpenAlexW3003473057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.